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August 2010: Of the Stomach and Gut

Infections: How the Kissing Disease Virus Hijacks Human Cells

( Source: MEDICA.de )

Photo: Lips [17/04/2014] University of Montreal researchers have discovered how a component of the Epstein Barr (EBV) virus takes over our cells gene regulating machinery, allowing the virus to replicate itself.Infections: How the Kissing Disease Virus Hijacks Human Cells - Read more

Tissue Engineering: Scientists Grow Cartilage to Reconstruct Nose

( Source: MEDICA.de )

Foto: Reconstructed cartilage [16/04/2014] Scientists at the University of Basel report first ever successful nose reconstruction surgery using cartilage grown in the laboratory. Cartilage cells were extracted from the patient’s nasal septum, multiplied and expanded onto a collagen membrane. The so-called engineered cartilage was then shaped according to the defect and implanted.Tissue Engineering: Scientists Grow Cartilage to Reconstruct Nose - Read more

Biotechnology: Sustainable Production of Compounds from Plants

( Source: MEDICA.de )

Photo: Madagascar periwinkle [14/04/2014] European scientists have made ground-breaking discoveries for improving the efficiency of the production of pharmaceuticals through plant biotechnology. Biotechnological production offers a cost-effective and environmentally friendly alternative to the chemical synthesis of rare and complex pharmaceutical compounds currently isolated from plants.Biotechnology: Sustainable Production of Compounds from Plants - Read more

Cells: A Step Forward in Adult Vertebrate Tissue Regeneration

( Source: MEDICA.de )

Photo: Zebrafish fin [01/04/2014] The reason why some animals can regenerate tissues after severe organ loss or amputation while others, such as humans, cannot renew some structures has always intrigued scientists. A research group from Instituto Gulbenkian de Ciência (IGC, Portugal) led by Joaquín Rodríguez León provided new clues to solve this central question.Cells: A Step Forward in Adult Vertebrate Tissue Regeneration - Read more

Analysis Method: Automatic Tracking of Biological Particles in Cell Microscopy Images

( Source: MEDICA.de )

Photo: Tracking result for virus particles [26/03/2014] In order to track the movements of biological particles in a cell, scientists at Heidelberg University and the German Cancer Research Center have developed a powerful analysis method for live cell microscopy images. This so-called probabilistic particle tracking method is automatic, computer-based and can be used for time-resolved two- and three-dimensional microscopy image data. Analysis Method: Automatic Tracking of Biological Particles in Cell Microscopy Images - Read more

New Project: Genetic Modification of Cancer Cells

( Source: MEDICA.de )

Photo: Structure of the Dnmt3a DNA methyl transferase [25/03/2014] Tumour cells shut down certain genes in the course of the progressing degeneration or mutate these, a process that considerably accelerates the growth of the tumour. An important role is played by DNA methyl transferase (Dnmts). A research group at the Chair for Biochemistry at the University of Stuttgart is investigating the influence of mutations in Dnmt3a, that are observed in many leukaemias.New Project: Genetic Modification of Cancer Cells - Read more

Alzheimer’s: How a Small Worm May Help the Fight

( Source: MEDICA.de )

Photo: Blue Roundworm [19/03/2014] Scientists at the Max Planck Institute (MPI) for Biology of Ageing in Cologne have found that a naturally occurring molecule has the ability to enhance defense mechanisms against neurodegenerative diseases. Feeding this particular metabolite to the small roundworm C. elegans helps clear toxic protein aggregates in the body and extends life span. Alzheimer’s: How a Small Worm May Help the Fight - Read more

Environment: Research Links Body Clocks to Chronic Lung Diseases

( Source: MEDICA.de )

Photo: Clock in the chest [19/03/2014] The body clock’s natural rhythm could be utilized to improve current therapies to delay the onset of chronic lung diseases. Scientists at the University of Manchester have discovered a rhythmic defense pathway in the lung controlled by our body clocks, which is essential to combat daily exposure to toxins and pollutants.Environment: Research Links Body Clocks to Chronic Lung Diseases - Read more

Genes: Key Heart-failure Culprit Discovered

( Source: MEDICA.de )

Photo: Heart muscle [14/03/2014] A team of cardiovascular researchers from Sanford-Burnham Medical Research Institute (Sanford-Burnham), the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai, and the University of California, San Diego have identified a small but powerful new player in the onset and progression of heart failure.Genes: Key Heart-failure Culprit Discovered - Read more

Semiconductor Material: Surface Characteristics Influence Cellular Growth

( Source: MEDICA.de )

Photo: Cell growing [13/03/2014] The finding stems from a study performed by researchers at North Carolina State University, the University of North Carolina at Chapel Hill (NCSU) and Purdue University, and may have utility for developing future neural implants.Semiconductor Material: Surface Characteristics Influence Cellular Growth - Read more

Chemical Reactions: The Thousand-droplets Test

( Source: MEDICA.de )

Photo: Droplets [28/02/2014] In the future, an entire chemistry lab could be accommodated in a tiny little droplet. While simple reactions already work in these simplest models of an artificial cell now a group of scientists of the Cluster of Excellence Nanosystems Initiative Munich (NIM) have established and investigated for the first time a complex biochemical system. Chemical Reactions: The Thousand-droplets Test - Read more

Tinnitus: Link between Loud Sounds and Hearing Loss

( Source: MEDICA.de )

Photo: Tinnitus [21/02/2014] University of Leicester research reveals why hearing loss is correlated with auditory signals failing to get transmitted along the auditory nerve. A research team investigating tinnitus has revealed new insights into the link between the exposure to loud sounds and hearing loss.Tinnitus: Link between Loud Sounds and Hearing Loss - Read more

Biofilms: Chips that Listen to Bacteria

( Source: MEDICA.de )

Photo: Biofilm [18/02/2014] A new study has demonstrated that integrated circuit technology, the basis of modern computers and communications devices, can be used for a most unusual application - the study of signaling in bacterial colonies.Biofilms: Chips that Listen to Bacteria - Read more

Infrared Microscopy: "We don’t know why certain pharmaceuticals bind especially well while others bind barely at all"

( Source: MEDICA.de )

[10/02/2014] Prof. Joachim Heberle from the Free University of Berlin wants to make the smallest protein structures visible under the microscope. He wants to accomplish this with an infrared microscope, originating in the field of physics. He told MEDICA.de which technology is behind all this and what he also wants to examine with it in the future.Infrared Microscopy: "We don’t know why certain pharmaceuticals bind especially well while others bind barely at all" - Read more

Infections: New Strategy to Combat Bacteria

( Source: MEDICA.de )

Photo: Bacteria [07/02/2014] Alvin Lo and Han Remaut (VIB/Vrije Universiteit Brussel) have identified a chemical substance with the potential of acting as a new drug to treat bacterial infections, particularly urinary tract infections.Infections: New Strategy to Combat Bacteria - Read more

Skin: Sweat Glands Heal Injuries

( Source: MEDICA.de )

Photo: Skin [05/02/2014] Our body’s sweat glands are a source of stem cells particularly suited to healing wounds – stem cells that form new skin cells and manage the healing process. They are not rejected by the body and can be obtained without a hospital stay.Skin: Sweat Glands Heal Injuries - Read more

Probe: A Quicker, Cheaper Way to Detect Staph in the Body

( Source: MEDICA.de )

Photo: Staph detector [04/02/2014] Researchers at the University of Iowa have created a noninvasive chemical probe that detects a common species of staph bacteria in the body.Probe: A Quicker, Cheaper Way to Detect Staph in the Body - Read more

Immune System: Body Kills 'Spontaneous' Blood Cancers on a Daily Basis

( Source: MEDICA.de )

Photo: Blood cells [04/02/2014] Immune cells undergo 'spontaneous' changes on a daily basis that could lead to cancers if not for the diligent surveillance of our immune system, Melbourne scientists have found.Immune System: Body Kills 'Spontaneous' Blood Cancers on a Daily Basis - Read more

Drugs: Geranium Extracts Inhibit HIV-1

( Source: MEDICA.de )

Photo: Pelargonium Sidoides [03/02/2014] Extracts of the geranium plant Pelargonium sidoides inactivate human immunodeficiency virus type 1 (HIV-1) and prevent the virus from invading human cells. Scientists from the Helmholtz Zentrum München report that these extracts represent a potential new class of anti-HIV-1 agents for the treatment of AIDS.Drugs: Geranium Extracts Inhibit HIV-1 - Read more

Surgery: “Our camera detects the tiniest remainder of a tumor”

( Source: MEDICA.de )

[03/02/2014] Differentiating tumor tissue from healthy tissue isn’t always easy for surgeons. Scattered cancer cells and early cancer are often hard to detect with the naked eye. A special camera now makes even the tiniest remainder of a tumor visible during surgery.Surgery: “Our camera detects the tiniest remainder of a tumor” - Read more

Skin Cells: Blood and Lymphatic Capillaries Grown for the First Time in the Lab

( Source: MEDICA.de )

Photo: (Graphic) Cross-section through the skin [31/01/2014] Researchers at the University Children’s Hospital Zurich and the University of Zurich have engineered skin cells for the very first time containing blood and lymphatic capillaries. They succeeded in isolating all the necessary types of skin cells from human skin tissue and engineering a skin graft that is similar to full-thickness skin.Skin Cells: Blood and Lymphatic Capillaries Grown for the First Time in the Lab - Read more

Cancer: Longer Screening Intervals with HPV-based Tests

( Source: MEDICA.de )

Photo: Laboratory analysis [24/01/2014] A new study from Karolinska Institutet in Sweden finds that testing for human papilloma virus (HPV) allows for longer time between screening tests when compared to cytology-based testing.Cancer: Longer Screening Intervals with HPV-based Tests - Read more

Microscopy: Faster Testing of New Pharmaceuticals

( Source: MEDICA.de )

Photo: The new microscope [23/01/2014] To improve medical treatment, researchers test new drug ingredients on biological cells. By combining two microscopy techniques, the time required for testing can be reduced by 50 to 80 percent. And far fewer measurements are needed.Microscopy: Faster Testing of New Pharmaceuticals - Read more

Immunology: „The immunosensory system goes beyond the actual immune cells“

( Source: MEDICA.de )

[22/01/2014] It guards the body but can become its enemy: the immune system defends us from intruding pathogens; it is also able to cause severe diseases if it falsely recognizes the body itself as a threat. Molecular receptors in the whole body enable the immune system to “sense” what happens within.Immunology: „The immunosensory system goes beyond the actual immune cells“ - Read more

Little but Lethal: Small RNAs Coordinate Bacterial Attack on Epithelial Cells

( Source: MEDICA.de )

Photo: Cell [14/01/2014] Two small RNAs (sRNAs) working in concert enable the deadly enterohemorrhagic Escherichia coli (EHEC) 0157:H7 to attach to and initiate infection in epithelial cells that line the digestive tract, according to a new study.Little but Lethal: Small RNAs Coordinate Bacterial Attack on Epithelial Cells - Read more

Infection: Virus Grows Tube to Insert DNA

( Source: MEDICA.de )

Photo: Tube-shaped Structure of a Virus [16/12/2013] Researchers have discovered a tube-shaped structure that forms temporarily in a certain type of virus to deliver its DNA during the infection process and then dissolves after its job is completed. Infection: Virus Grows Tube to Insert DNA - Read more

New Online Platform: The Oracle of the T Cell

( Source: MEDICA.de )

Photo:Virtual T-Cell [06/12/2013] A new online platform predicts how the human immune system reacts to foreign substances.New Online Platform: The Oracle of the T Cell - Read more

Cancer: Researchers Find Shape-shifting Stops Migrating Cells

( Source: MEDICA.de )

Photo: Fried Egg [05/12/2013] Like a car with a front and back end, a steering mechanism and an engine to push it forward, cancer cells propel themselves through normal tissues and organs to spread cancer throughout the body. Researchers at Mayo Clinic in Florida have managed to turn these cells into shapes like a round fried egg and an exaggerated starfish that sticks out in many directions — both of which cannot now move.Cancer: Researchers Find Shape-shifting Stops Migrating Cells - Read more

Virtual training: "Students gladly accept the flexible learning option"

( Source: MEDICA.de )

[01/12/2013] Instead of just sitting in front of a microscope, Bavarian medical students now also sit at the computer and categorize different tissue types. This is made possible by a project between the Universities and the Fraunhofer Institute for Integrated Circuits IIS. MEDICA.de spoke with Associate Professor Thomas Wittenberg about the benefits of virtual training.Virtual training: "Students gladly accept the flexible learning option" - Read more

Laboratory: Coumarins Show Potency against Inflammations

( Source: MEDICA.de )

Photo: Cinnamon [26/11/2013] New methods for the laboratory-scale synthesis of coumarin-based drugs were developed in a recent study completed at the University of Eastern Finland.Laboratory: Coumarins Show Potency against Inflammations - Read more

Genes: Regulation through Argonaute Proteins

( Source: MEDICA.de )

Photo: Puzzle pieces [15/11/2013] Heidelberg scientists identify protein motifs that influence gene silencing.Genes: Regulation through Argonaute Proteins - Read more

Pacemaker Cells: The Heart’s Metronome

( Source: MEDICA.de )

Photo: Conductor's baton [14/11/2013] A specific cell population is responsible for ensuring that our heartbeat remains regular. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have now elucidated the mode of action of one of the crucial components of the heart’s intrinsic pacemaker.Pacemaker Cells: The Heart’s Metronome - Read more

Immune System: Bacterial Toxin Sets the Course for Infection

( Source: MEDICA.de )

Photo: Yersinia [12/11/2013] Every year gastro-intestinal diseases have lethal consequences for more than five million individuals. Researchers from Braunschweig have now discovered what makes a specific strain of Yersinia pseudotuberculosis–one of the main instigators for these infections–so dangerous.Immune System: Bacterial Toxin Sets the Course for Infection - Read more

Colon Cancer: Microbes in the Gut Help Determine Risk of Tumors

( Source: MEDICA.de )

Photo: Mice [05/11/2013] Transferring the gut microbes from a mouse with colon tumors to germ-free mice makes those mice prone to getting tumors as well. The work has implications for human health because it indicates the risk of colorectal cancer may well have a microbial component.Colon Cancer: Microbes in the Gut Help Determine Risk of Tumors - Read more

Cancer: Nano Capsules Kill Tumor Cells

( Source: MEDICA.de )

Photo: Nano capsules [28/10/2013] Chemotherapy is often preferred for fighting cancer, but its side effects can be considerable. A new technique may reduce these in future: nanoparticle-encapsulated substances could kill off tumor cells selectively. This will be easier on patients.Cancer: Nano Capsules Kill Tumor Cells - Read more

Liver: New Regulator of Drug Detoxification Discovered

( Source: MEDICA.de )

Photo: Liver damage [14/10/2013] A CNIO group led by researcher Erwin Wagner discovered that the Fra-1 protein is causally involved in liver fibrosis and protects the liver from drug-induced liver damage.Liver: New Regulator of Drug Detoxification Discovered - Read more

Narcolepsy: How the Muscles Accidentally Fall Asleep

( Source: MEDICA.de )

Photo: Man sleeping [11/10/2013] Scientists at the University of Toronto shed light on the brain mechanisms behind a debilitating sleep disorder.Narcolepsy: How the Muscles Accidentally Fall Asleep - Read more

“Our plasma promotes cell growth”

( Source: MEDICA.de )

[08/10/2013] In the world of medicine, the term plasma is often associated with a liquid. For physicists and chemists however, plasma is a gaseous state. Now researchers at the Fraunhofer Institute for Surface Engineering and Thin Films (IST) together with physicians from the Helmholtz Center for Infection Research (HZI) have developed plasma that lets cells grow on the surface of a bag.“Our plasma promotes cell growth” - Read more

Molecules: Promise for New Anti-flu Medicines

( Source: MEDICA.de )

Photo: Chemical compound [04/10/2013] A new way to attack flu viruses is taking shape in laboratories at Rutgers University, where scientists have identified chemical agents that block the virus's ability to replicate itself in cell culture.Molecules: Promise for New Anti-flu Medicines - Read more

Chip: Liquid Biopsy Could Improve Cancer Diagnosis

( Source: MEDICA.de )

Photo: Liquid Biopsy [02/10/2013] A microfluidic chip developed at the University of Michigan is among the best at capturing elusive circulating tumor cells from blood - and it can support the cells' growth for further analysis.Chip: Liquid Biopsy Could Improve Cancer Diagnosis - Read more

Complex Diseases: New Genetic Map

( Source: MEDICA.de )

Photo: Complex Diseases [02/10/2013] Now, scientists from the University of Chicago have created one of the most expansive analyses to date of the genetic factors at play in complex diseases—by using diseases with known genetic causes to guide them.Complex Diseases: New Genetic Map - Read more

Skin: Important Wound-Healing Process Discovered

( Source: MEDICA.de )

Photo: Wound healing [01/10/2013] Scientists at The Scripps Research Institute (TSRI) have discovered an important process by which special immune cells in the skin help heal wounds.Skin: Important Wound-Healing Process Discovered - Read more

Pancreas: The Immune System Fights Cancer

( Source: MEDICA.de )

Photo: Pancreas [01/10/2013] A new study reveals separate tumor sites respond differently to a new immunotherapy. This highlights the power of a new real-time imaging technique to study response.Pancreas: The Immune System Fights Cancer - Read more

Bacteria: Optimal Production of Proteins

( Source: MEDICA.de )

Photo: Bacteria [27/09/2013] 'Just in time' - not only cars are being built according to this principle nowadays. Aircraft, mobile phones and computers are also produced following this method, in which all components are delivered exactly at the time when they are needed. This saves storage capacity and therefore cash. Hence it is supposed to be particularly efficient.Bacteria: Optimal Production of Proteins - Read more

Type 1 Diabetes: New Islet Cell Transplant Procedure

( Source: MEDICA.de )

Foto: Diabetes [26/09/2013] The latest approach to islet transplantation, in which clusters of insulin-producing cells known as islets are transplanted from a donor pancreas into another person's liver, has produced substantially improved results for patients with type 1 diabetes.Type 1 Diabetes: New Islet Cell Transplant Procedure - Read more

Brain: Researchers Gain New Insights

( Source: MEDICA.de )

Foto: Microscopic view of the entorhinal cortex [24/09/2013] The entorhinal cortex is a link between the brain's memory centre, the hippocampus, and the other areas of the brain. It is, however, more than an interface that only transfers nervous impulses. Brain: Researchers Gain New Insights - Read more

Immun Defense: Novel Mechanism Discovered In First Line

( Source: MEDICA.de )

Photo: Medicine [12/09/2013] A discovery by Scientists from A*STAR’s Singapore Immunology Network (SIgN) opens doors to developing new therapies to eradicate tumour cells and combat infections.Immun Defense: Novel Mechanism Discovered In First Line - Read more

Mechanobiology: Understanding the Mechanics of Cells

( Source: MEDICA.de )

Photo: Cells [05/09/2013] University of Southampton researchers are at the forefront of research into mechanobiology, an emerging field of science combining biology and engineering, which investigates the influence of mechanical forces on cellular and molecular processes.Mechanobiology: Understanding the Mechanics of Cells - Read more

Brain: Researchers Generate Myelin from Stem Cells

( Source: MEDICA.de )

Photo: Myelin [30/08/2013] New findings hold promise for developing regenerative therapies for spinal cord injuries and diseases such as multiple sclerosis.Brain: Researchers Generate Myelin from Stem Cells - Read more

Cell Structure: A Skeleton for Chromosomes

( Source: MEDICA.de )

Photo: Cell nucleus [26/08/2013] Jan-Michael Peters and his team at the Research Institute of Molecular Pathology (IMP) found that the structure of Chromosomes is supported by a kind of molecular skeleton, made of cohesin. Cell Structure: A Skeleton for Chromosomes - Read more

Cancer: Improved Effectiveness of Chemotherapy

( Source: MEDICA.de )

Photo: Tumor cell [16/08/2013] Cancer cells often develop defense mechanisms to survive chemotherapy. A group of researchers from the Institutes of Pharmacology and Pathology in Bern present new solutions for preventing the development of such resistances.Cancer: Improved Effectiveness of Chemotherapy - Read more

Immune System: Lymph Nodes with Location Memory

( Source: MEDICA.de )

Photo: Cells [15/08/2013] Regulatory T cells (or Tregs for short) guide all of the other immune cells. How Tregs become Tregs in the first place has been only incompletely understood – until now. Scientists have recently gleaned important new insights into the workings of these cells.Immune System: Lymph Nodes with Location Memory - Read more

Atherosclerosis: Macrophage Proliferation Furthers Progression

( Source: MEDICA.de )

Photo: Cholesterol [13/08/2013] New insights into the development of vulnerable atherosclerotic plaques could lead to better treatment or prevention of heart attacks and strokes.Atherosclerosis: Macrophage Proliferation Furthers Progression - Read more

Biomedicine: Protein Profile of Tumor Cells Decoded

( Source: MEDICA.de )

Photo: Protein signatures [09/08/2013] Since proteins are responsible for converting somatic cells into tumor cells, scientists have now decoded the proteome of 59 tumor cell lines – and have found new ways to explain why cancer drugs do not have the same effect on all patients.Biomedicine: Protein Profile of Tumor Cells Decoded - Read more

Hydrogels: Algae Polymer Ribbons for Better Healing

( Source: MEDICA.de )

Photo: Endothelial cells [29/07/2013] Freiburg researchers have developed novel hydrogels for tissue regeneration that promotes the proper organization of human cells and that can be fine-tuned to fit any body part.Hydrogels: Algae Polymer Ribbons for Better Healing - Read more

Hydrogel: A New Approach for Studying Brain Cancer

( Source: MEDICA.de )

Photo: Cancer cells [25/07/2013] A team of engineers has developed a three-dimensional hydrogel that closely mimics conditions in the brain. The new approach allows the researchers to selectively tune the malignancy of brain cancer cells they study.Hydrogel: A New Approach for Studying Brain Cancer - Read more

HIV: Platelets Protect Cells

( Source: MEDICA.de )

Photo: Cell and virus [25/07/2013] Scientists of the German Primate Center (DPZ) have shown that platelet activation inhibits the host cell entry of HIV.HIV: Platelets Protect Cells - Read more

Transplantation: A Step towards Custom-built Blood Vessels

( Source: MEDICA.de )

Photo: Blood vessels [18/07/2013] Researchers at John Hopkins have coaxed stem cells into forming networks of new blood vessels in the laboratory, then successfully transplanted them into mice.Transplantation: A Step towards Custom-built Blood Vessels - Read more

Pain: New Compound Promising as Opioid Alternative

( Source: MEDICA.de )

Photo: Formula [17/07/2013] A drug targeting a protein complex containing two different types of opioid receptors may be an effective alternative to morphine and other opioid pain medications.Pain: New Compound Promising as Opioid Alternative - Read more

Diabetes: Interspecies Transplant of Islet Cells

( Source: MEDICA.de )

Photo: Mouse [16/07/2013] In the first step toward animal-to-human transplants of insulin-producing cells for people with type 1 diabetes, Northwestern Medicine scientists have successfully transplanted islet cells from one species to another. Diabetes: Interspecies Transplant of Islet Cells - Read more

Disease Research: Stem Cell Clues Uncovered

( Source: MEDICA.de )

Photo: Fruit fly testis [15/07/2013] Proper tissue function and regeneration is supported by stem cells, which reside in so-called niches. New work from Carnegie's Yixian Zheng and Haiyang Chen identifies an important component for regulating stem cell niches, with impacts on tissue building and function. The results could have implications for disease research.Disease Research: Stem Cell Clues Uncovered - Read more

Colon Cancer: Soy Peptide May Reduce Metastasis

( Source: MEDICA.de )

Photo: Soy products [10/07/2013] After learning that injection of the soy peptide lunasin dramatically reduced colon cancer metastasis in mice, researchers were eager to see how lunasin as part of a daily diet would affect metastasis.Colon Cancer: Soy Peptide May Reduce Metastasis - Read more

Cells: Technological Breakthrough for Better Drugs

( Source: MEDICA.de )

Photo: Path of drugs [08/07/2013] Researchers at Karolinska Institutet in Sweden have developed the first method for directly measuring the extent to which drugs reach their targets in the cell. The method could make a significant contribution to the development of new, improved drug substances.Cells: Technological Breakthrough for Better Drugs - Read more

Infections: The Body Aids and Abets Cancer Spread

( Source: MEDICA.de )

Photo: Cancer cells [04/07/2013] A current study, led by the Research Institute of the McGill University Health Centre (RI-MUHC), reveal that white blood cells play a role in activating cancer cells and facilitating their spread to secondary tumors.Infections: The Body Aids and Abets Cancer Spread - Read more

Diagnostics: Cell Separation in Microchannels

( Source: MEDICA.de )

[24/06/2013] Cancer is a malicious disease: Even after a tumor has been removed, cancer cells may still be circulating through the blood and cause metastases in other organs. These cells have to be detected early, since metastases drastically reduce the chances of recovery. A newly developed cell separation system may be able make diagnoses more reliable.Diagnostics: Cell Separation in Microchannels - Read more

Oncology: Using Math to Kill Cancer Cells

( Source: MEDICA.de )

Photo: Math [17/06/2013] Researchers outline how advanced mathematical modelling can be used in the fight against cancer. The technique predicts how different treatments and genetic modifications might allow cancer-killing, oncolytic viruses to overcome the natural defences that cancer cells use to stave off viral infection.Oncology: Using Math to Kill Cancer Cells - Read more

Gene Therapy: Virus Restores Sight

( Source: MEDICA.de )

Photo: Gene Therapy [14/06/2013] Researchers at the University of California, Berkeley, have developed a new method to insert genes into eye cells that could greatly expand gene therapy to help restore sight to patients with blinding diseases.Gene Therapy: Virus Restores Sight - Read more

Genetics: Hearing Loss Clue Uncovered

( Source: MEDICA.de )

Photo: Ear [13/06/2013] A novel genetic mutation was first identified in 2010 as causing hearing loss in humans. Researchers have now discovered that this mutation induces malfunction of an inhibitor of an enzyme commonly found in our body that destroys proteins.Genetics: Hearing Loss Clue Uncovered - Read more

Cerebral Cortex: 3-D Map of Blood Vessels

( Source: MEDICA.de )

Photo: Blood vessel [10/06/2013] Blood vessels within a sensory area of the mammalian brain loop and connect in unexpected ways, a new map has revealed. The study describes vascular architecture within a well-known region of the cerebral cortex and explores what that structure means for functional imaging of the brain and the onset of a kind of dementia.Cerebral Cortex: 3-D Map of Blood Vessels - Read more

New Technique: Protein Drugs From Bacteria

( Source: MEDICA.de )

Photo: Bacteria [06/06/2013] A cheaper, more efficient technique for developing complex protein drugs from bacteria has been developed at the University of Sheffield.New Technique: Protein Drugs From Bacteria - Read more

Multiple Sclerosis: Enhanced White Blood Cells Heal Mice

( Source: MEDICA.de )

Photo: Damaged cells [03/06/2013] Genetically engineered immune cells seem to promote healing in mice infected with a neurological disease similar to multiple sclerosis (MS), cleaning up lesions and allowing the mice to regain use of their legs and tails.Multiple Sclerosis: Enhanced White Blood Cells Heal Mice - Read more

Cells: Tumor-activated Protein Promotes Cancer Spread

( Source: MEDICA.de )

Photo: Metastasis [15/05/2013] Researchers at the University of California report that cancers physically alter cells in the lymphatic system – a network of vessels that transports and stores immune cells throughout the body – to promote the spread of disease, a process called metastasis.Cells: Tumor-activated Protein Promotes Cancer Spread - Read more

Nerves: Reversing Paralysis with Restorative Gel

( Source: MEDICA.de )

Photo: Nerve cells connect [14/05/2013] Some parts of the body, like the liver, can regenerate themselves after damage. But others, such as our nervous system, are considered either irreparable or slow to recover, leaving thousands with a lifetime of pain, limited mobility, or even paralysis.Nerves: Reversing Paralysis with Restorative Gel - Read more

Cancer Cells: Stability for the Genome

( Source: MEDICA.de )

Photo: DNA [10/05/2013] In cancer cells, the genome is often in a chaotic, unstable state. Now, a research group from the Würzburg Biocenter, Germany, found out which enzymes can stabilize DNA.Cancer Cells: Stability for the Genome - Read more

Matrix: Cells Control Neuronal Connections

( Source: MEDICA.de )

Photo: Neuron in the net [07/05/2013] Environment moulds behaviour - and not just that of people in society, but also at the microscopic level. This is because, for their function, neurons are dependent on the cell environment, the so-termed extracellular matrix. Matrix: Cells Control Neuronal Connections - Read more

Genetics: The Many Faces of the Bacterial Defense System

( Source: MEDICA.de )

Photo: Bacteria [02/05/2013] Even bacteria have a kind of immune system they use to defend themselves against unwanted intruders – in their case, viruses. Scientists at the Helmholtz Center for Infection Research (HZI) in Braunschweig, Germany, were now able to show that this defense system is much more diverse than previously thought and that it comes in multiple versions.Genetics: The Many Faces of the Bacterial Defense System - Read more

Cells: Conversion from Bad Fat to Good Fat

( Source: MEDICA.de )

Photo: Fat cells [29/04/2013] Scientists from Swiss Federal Institute of Technology (ETH) Zurich have shown for the first time that brown and white fat cells in a living organism can be converted from one cell type to the other.Cells: Conversion from Bad Fat to Good Fat - Read more

Leukemia: High Treatment Costs Harming Patients

( Source: MEDICA.de )

Photo: Blood clots [29/04/2013] The increasing cost of treatments for chronic myeloid leukemia (CML) in the United States has reached unsustainably high levels and may be leaving many patients under- or untreated because they cannot afford care, according to a study.Leukemia: High Treatment Costs Harming Patients - Read more

Children: Detecting Autism from Brain Activity

( Source: MEDICA.de )

Photo: Brain [19/04/2013] Neuroscientists from Case Western Reserve University School of Medicine and the University of Toronto have developed an efficient and reliable method of analyzing brain activity to detect autism in children.Children: Detecting Autism from Brain Activity - Read more

Cell Division: How Alzheimer's Could Occur

( Source: MEDICA.de )

Photo: Spherical structures in cells [12/04/2013] A new hypothesis has been developed by researchers from the Ruhr-Universität Bochum (RUB) on how Alzheimer's disease could occur. They analyzed the interaction of the proteins FE65 and BLM that regulate cell division.Cell Division: How Alzheimer's Could Occur - Read more

Copper: The New Building Block in Hospital Hygiene

( Source: MEDICA.de )

Photo: Copper handles [10/04/2013] Germs can be easily transmitted from person to person in hospitals. This is especially dangerous for patients when their immune system is weakened by an existing disease or not yet fully developed, as is the case with children.Copper: The New Building Block in Hospital Hygiene - Read more

Light: Moving Cells Holds Medical Promise

( Source: MEDICA.de )

Photo: Immune cell [09/04/2013] Scientists at Washington University School of Medicine in St. Louis have shown they can coax cells to move toward a beam of light. The feat is a first step toward manipulating cells to control insulin secretion or heart rate using light.Light: Moving Cells Holds Medical Promise - Read more

New Device: Capture of Circulating Tumor Cells

( Source: MEDICA.de )

Photo: Device [04/04/2013] A new system for isolating rare circulating tumor cells (CTCs) – living solid tumor cells found at low levels in the bloodstream – shows significant improvement over previously developed devices and does not require prior identification of tumor-specific target molecules.New Device: Capture of Circulating Tumor Cells - Read more

Stem Cells: Development Depends On Grip

( Source: MEDICA.de )

Photo: Model of bone-like cell [02/04/2013] Researchers have generated new insight on how a stem cell's environment influences its development: Whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can "grip" the material they are growing in.Stem Cells: Development Depends On Grip - Read more

Directly in the Brain: New Nerve Cells Formed

( Source: MEDICA.de )

Photo: Brain cells [28/03/2013] The field of cell therapy, which aims to form new cells in the body in order to cure disease, has taken another important step in the development towards new treatments. A new report from researchers at Lund University in Sweden shows that it is possible to re-programme other cells to become nerve cells, directly in the brain.Directly in the Brain: New Nerve Cells Formed - Read more

Immune System: The Fates of Individual T Cells

( Source: MEDICA.de )

Photo: Immune cell [21/03/2013] By charting the differing fates of individual T cells, researchers have shown that previously unpredictable aspects of the adaptive immune response can be effectively modeled.Immune System: The Fates of Individual T Cells - Read more

Blood: Macrophages Control Red Blood Cells

( Source: MEDICA.de )

Photo: Macrophage and red blood cell [19/03/2013] Researchers at Albert Einstein College of Medicine and the Icahn School of Medicine at Mount Sinai have found that macrophages – white blood cells that play a key role in the immune response – also help to both produce and eliminate red blood cells.Blood: Macrophages Control Red Blood Cells - Read more

Laser Scalpel: Current Research Promises Gentle Surgery

( Source: MEDICA.de )

[13/03/2013] [Intro:] The Picosecond Infrared Laser (PIRL), which was developed at the University Medical Center Hamburg-Eppendorf (UKE), is intended to precisely cut down to the cell when used as a laser scalpel. During surgery, it avoids injuries to nerves or blood vessels and barely leaves any scarring.Laser Scalpel: Current Research Promises Gentle Surgery - Read more

Cell Death: Discovery of Destructive Protein

( Source: MEDICA.de )

Photo: Neuroprotection [12/03/2013] Oxidative stress turns a protein that normally protects healthy cells into their executioner, according to a current study. This discovery could help scientists develop therapies to combat a host of conditions from stroke to Lou Gehrig's disease.Cell Death: Discovery of Destructive Protein - Read more

Proteins: A Scanner for Hereditary Defects

( Source: MEDICA.de )

Graphic [25/01/2013] The body’s own proteins continually scour the genetic material for signs of damage. Researchers from the Institute of Veterinary Pharmacology and Toxicology at the University of Zurich see new possibilities in this damage recognition for improving cancer treatment in humans.Proteins: A Scanner for Hereditary Defects - Read more

Neurology: Oxygen Chamber Can Boost Brain Repair

( Source: MEDICA.de )

Photo: Brain [24/01/2013] Doctor Shai Efrati of Tel Aviv University has found a way to restore a significant amount of neurological function in brain tissue thought to be chronically damaged — even years after initial injury.Neurology: Oxygen Chamber Can Boost Brain Repair - Read more

Molecular Forces: Key to Proper Cell Division

( Source: MEDICA.de )

Photo: Chromokinesin [22/01/2013] Studies led by cell biologist Thomas Maresca at the University of Massachusetts Amherst are revealing new details about a molecular surveillance system that helps detect and correct errors in cell division that can lead to cell death or human diseases.Molecular Forces: Key to Proper Cell Division - Read more

Brain: One Form of Neuron Turned into Another

( Source: MEDICA.de )

Photo: Brain [21/01/2013] A new finding by Harvard stem cell biologists turns one of the basics of neurobiology on its head – demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.Brain: One Form of Neuron Turned into Another - Read more

Seeing: Specific Protein Essential for Healthy Eyes

( Source: MEDICA.de )

Photo: Eye [07/01/2013] Researchers have found that a specific protein is essential not only for maintaining a healthy retina in the eye, but also may have implications for understanding and possibly treating other conditions in the immune, reproductive, vascular and nervous systems and in various cancers.Seeing: Specific Protein Essential for Healthy Eyes - Read more

Neurons: Pair of Proteins Gets Brain Cells into Shape

( Source: MEDICA.de )

Photo: Nerve cells [21/12/2012] Scientists at the German Center for Neurodegenerative Diseases (DZNE) in Bonn have gained new insights into the early phase of the brain’s development. They identified two proteins that control the formation of cell protuberances. The typical ramifications through which nerve cells receive and forward signals ultimately originate from these outgrowths.Neurons: Pair of Proteins Gets Brain Cells into Shape - Read more

Neurons: ”The project’s goal is to grow three-dimensional neural tissue“

( Source: MEDICA.de )

[21/12/2012] The international partners of the “3D-NeuroN” research project want to cultivate nerve tissue in three dimensions. German researchers are working on micro sensors with which they want to measure and evaluate electrical activity of neurons in three-dimensional cell cultures.Neurons: ”The project’s goal is to grow three-dimensional neural tissue“ - Read more

Brain: Silent Stroke Can Cause Parkinson's Disease

( Source: MEDICA.de )

Photo: MRI images [20/12/2012] Scientists at The University of Manchester have for the first time identified why a patient who appears outwardly healthy may develop Parkinson's disease.Brain: Silent Stroke Can Cause Parkinson's Disease - Read more

Neurology: Hybrid Tunnel Guides Severed Nerves

( Source: MEDICA.de )

Photo: Nerve cell and hybrid tunnel [19/12/2012] Building a tunnel made up of both hard and soft materials to guide the reconnection of severed nerve endings may be the first step toward helping patients with extensive nerve trauma regain feeling and movement.Neurology: Hybrid Tunnel Guides Severed Nerves - Read more

Genes: Heart Cells Become 'Biological Pacemakers'

( Source: MEDICA.de )

Photo: Heart cells [17/12/2012] Cedars-Sinai Heart Institute researchers have reprogrammed ordinary heart cells to become exact replicas of highly specialized pacemaker cells by injecting a single gene (Tbx18) – a major step forward in the search for a biological therapy to correct erratic heartbeats.Genes: Heart Cells Become 'Biological Pacemakers' - Read more

Biopolymer: Interfacing Biological and Artificial Systems

( Source: MEDICA.de )

Photo: Polymer [14/12/2012] In their recently published article researchers from the University of Tokyo describe how developments in synthesis techniques have liberated the polymer MPC’s potential for a huge range of medical and biological applications.Biopolymer: Interfacing Biological and Artificial Systems - Read more

Neuroscience: Ultrasound Can Stimulate Different Sensations

( Source: MEDICA.de )

Photo: Ultrasound [07/12/2012] A century after the world’s first ultrasonic detection device, Virginia Tech Carilion Research Institute scientists have provided the first neurophysiological evidence for something that researchers have long suspected: ultrasound applied to the periphery, such as the fingertips, can stimulate different sensory pathways leading to the brain.Neuroscience: Ultrasound Can Stimulate Different Sensations - Read more

Seeing: New Technique for Stem Cell Therapy

( Source: MEDICA.de )

Photo: Disc of biodegradable material [06/12/2012] Researchers from the University of Sheffield show a new method for producing membranes to help in the grafting of stem cells onto the eye, mimicking structural features of the eye itself. Seeing: New Technique for Stem Cell Therapy - Read more

Brain: Precisely Engineering Tissue in 3D

( Source: MEDICA.de )

Photo: Nerve cells [03/12/2012] Borrowing from microfabrication techniques used in the semiconductor industry, MIT and Harvard Medical School (HMS) engineers have developed a simple and inexpensive way to create three-dimensional brain tissues in a lab dish.Brain: Precisely Engineering Tissue in 3D - Read more

Neurophysiology: “The body’s memory has an impact on neurological memory”

( Source: MEDICA.de )

[03/12/2012] Our behavior is reflected in our body. Poor nutrition or addictions affect body functions and leave their mark on the body’s memory. The neurological memory also works similarly: the nervous system stores the traces of the signaling pathways in cells and recalls them as required.Neurophysiology: “The body’s memory has an impact on neurological memory” - Read more

T Cells: Traffic Cops of the Immune System

( Source: MEDICA.de )

Photo: Localization of IkBNS in the cell [30/11/2012] A certain type of immune cell – the regulatory T cell, or Treg for short – is in charge of putting on the brakes on the immune response. In a way, this cell type might be considered the immune system’s traffic cop. Now, German scientists have looked into the origin of Tregs and uncovered a central role played by the protein IκBNS.T Cells: Traffic Cops of the Immune System - Read more

Influenza: Replication Machinery of Viruses Described

( Source: MEDICA.de )

Photo: Influenza virus [23/11/2012] Scientists at The Scripps Research Institute (TSRI) have made a major advance in understanding how flu viruses replicate within infected cells.Influenza: Replication Machinery of Viruses Described - Read more

Damaged Nerve Cells: Step Forward in Regenerating and Repairing

( Source: MEDICA.de )

Photo: Nerve cells [23/11/2012] A team of researchers from the Institut de recherches cliniques de Montréal (IRCM), led by Doctor Frédéric Charron, recently uncovered a nerve cell’s internal clock, used during embryonic development.Damaged Nerve Cells: Step Forward in Regenerating and Repairing - Read more

Nanoprobes: Bright Light Reveals Location of Target Tissues

( Source: MEDICA.de )

Photo: BRIGHT and cell [22/11/2012] Called BRIGHTs, tiny probes bind to biomarkers of disease and, when swept by an infrared laser, light up to reveal their location. The probes consist of gold nanoparticles covered with molecules called Raman reporters.Nanoprobes: Bright Light Reveals Location of Target Tissues - Read more

MEDICA 2012: „We are very pleased with the fair. We had lots of visitors at our stand every day”

( Source: MEDICA.de )

[22/11/2012] CompuGroup Medical is one of the biggest exhibitors on MEDICA from the field of medical IT. In this year again, they have presented their products and solutions at a shared stand in hall 15. In the concluding interview from the last fair day, Volker Hess, Head of Marketing & Communications CER of CompuGroup Medical, told MEDICA.de that he is very pleased with the way the trade fair has gone.MEDICA 2012: „We are very pleased with the fair. We had lots of visitors at our stand every day” - Read more

Heart Attack: Hope for Regeneration Through Progenitor Cells

( Source: MEDICA.de )

Photo: Mouse heart cells [21/11/2012] A research team of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB has discovered cell surface markers that enable the identification and isolation of living functional cardiovascular progenitor cells (CPCs).Heart Attack: Hope for Regeneration Through Progenitor Cells - Read more

Nanotechnology: Synthetic Cell Membrane Channels Made of DNA

( Source: MEDICA.de )

Photo: Membrane channel [21/11/2012] Physicists at the Technische Universitaet Muenchen (TUM) and the University of Michigan have shown that synthetic membrane channels can be constructed through "DNA nanotechnology."Nanotechnology: Synthetic Cell Membrane Channels Made of DNA - Read more

Stroke: When Helper Cells Become Harmful

( Source: MEDICA.de )

Photo: MRI-Images [19/11/2012] In case of strokes, the immune system contributes to the brain injury. Scientists of the Universities of Würzburg and Münster, Germany, now show for the first time in which way certain T helper cells are involved in the process.Stroke: When Helper Cells Become Harmful - Read more

Brain Implantat: Slim Electrode Cozies Up to Single Neurons

( Source: MEDICA.de )

Photo: Neuron [14/11/2012] A thin, flexible electrode developed at the University of Michigan is ten times smaller than the nearest competition and could make long-term measurements of neural activity practical at last. Brain Implantat: Slim Electrode Cozies Up to Single Neurons - Read more

Hepatitis C: A ‘Finger’ Pointing the Way to New Medication

( Source: MEDICA.de )

Photo: HCV-infected cells [12/11/2012] Researchers at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany, have discovered new drug leads that are efficient against resistant virus like HCV.Hepatitis C: A ‘Finger’ Pointing the Way to New Medication - Read more

Aging: Fat Molecule Ceramide May Factor in Muscle Loss

( Source: MEDICA.de )

Photo: Model of human muscles [02/11/2012] A small study of older and younger men conducted at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University suggests that a build-up of a fat molecule known as ceramide might play a leading role in muscle deterioration in older adults.Aging: Fat Molecule Ceramide May Factor in Muscle Loss - Read more

Leukemia: Therapeutic Targets Identified

( Source: MEDICA.de )

Photo: Leukemia cells [30/10/2012] New insight into the aggressive behavior of certain adult B-acute lymphoblastic leukemias has provided researchers with a potential new prognostic biomarker and a promising new therapeutic target.Leukemia: Therapeutic Targets Identified - Read more

Parkinson’s Disease: Stimulating Brain Cells with Light

( Source: MEDICA.de )

Photo: Nerve cells [29/10/2012] Introducing a light-sensitive protein in transgenic nerve cells or transplanting nerve cells into the brains of laboratory animals to combat Parkinson’s disease – these events may sound like science fiction but they are soon to become a reality in Lund University in Sweden.Parkinson’s Disease: Stimulating Brain Cells with Light - Read more

Genetic: "Mechanically Active" DNA Material

( Source: MEDICA.de )

Photo: Typical DNA gel used for the study [25/10/2012] Artificial muscles and self-propelled goo may be the stuff of Hollywood fiction, but for scientists from University of California Santa Barbara (UCSB), the reality of it is not that far away. By blending their areas of expertise, the pair have created a dynamic gel made of DNA that mechanically responds to stimuli in much the same way that cells do.Genetic: "Mechanically Active" DNA Material - Read more

No Advantage: Blood Stem Cells Versus Bone Marrow

( Source: MEDICA.de )

Photo: Blood cells [22/10/2012] Doctor Claudio Anasetti of the Department of Blood & Marrow Transplant at Moffitt Cancer Center, and colleagues from 47 research sites conducted a two-year clinical trial comparing two-year survival probabilities for patients transplanted with peripheral blood stem cells or bone marrow stem cells from unrelated donors.No Advantage: Blood Stem Cells Versus Bone Marrow - Read more

Inheritance: New Findings About Mitchondrial Diseases

( Source: MEDICA.de )

Photo: Mitochondria [09/10/2012] Researchers from the Max Planck Institute for Biology of Aging discovered, how and when mitochondrial diseases are inherited, using a new model. This is decided when the future mother herself is still an embryo.Inheritance: New Findings About Mitchondrial Diseases - Read more

Anti-Aiging: Nanoparticles Against Aging

( Source: MEDICA.de )

Photo: Nanoparticles [05/10/2012] A team of Spanish scientists of the Asociación RUVID has developed an intelligent nanodevice that lays the foundations for the future development of new therapies against aging. The device consists of nanoparticles that can selectively release drugs in aged human cells. Anti-Aiging: Nanoparticles Against Aging - Read more

Viruses: How Immune Cells Defend Themselves Against HIV

( Source: MEDICA.de )

Photo: HIV [27/09/2012] A team of scientists led by virologists Professor Oliver T. Fackler and Professor Oliver T. Keppler from Heidelberg University Hospital, Germany, have decoded a mechanism used by the human immune system to protect itself from HIV viruses.Viruses: How Immune Cells Defend Themselves Against HIV - Read more

Blood Cancer: Double Assault on Tough Types of Leukemias

( Source: MEDICA.de )

Photo: Leukemia [24/09/2012] Investigators at Northwestern University Feinberg School of Medicine have identified two promising therapies to treat patients with acute megakaryocytic leukemia (AMKL), a rare form of leukemia where the number of cases is expected to increase with the aging population.Blood Cancer: Double Assault on Tough Types of Leukemias - Read more

Immune Cells: Puzzle of B-Cell Lymphoma Development Solved

( Source: MEDICA.de )

Photo: Germinal center [24/09/2012] Doctor Dinis Pedro Calado and Doctor Klaus Rajewsky of the Max Delbrück Center (MDC) have identified subgroups of B cells in germinal centers in which the proto-oncogene Myc, a critical regulator of cellular proliferation, is highly activated.Immune Cells: Puzzle of B-Cell Lymphoma Development Solved - Read more

Fasting: “People take a reserved stance towards naturopathic procedures"

( Source: MEDICA.de )

[24/09/2012] When people talk about fasting, they often mean caloric restriction in terms of a dietary regimen. Yet medically supervised fasting is so much more than this. Fasting has a positive effect on the human body in many different ways and could provide new perspectives for chronically sick people in the future. What mechanisms are behind all this – what is psychology and what is scientifically proven?Fasting: “People take a reserved stance towards naturopathic procedures" - Read more

Nanoparticles: Boosting Efficacy of Drugs

( Source: MEDICA.de )

Photo: Researcher [20/09/2012] Nanoparticles have shown great promise in the targeted delivery of drugs to cells, but researchers at the University of Georgia have refined the drug delivery process further by using nanoparticles to deliver drugs to a specific organelle within cells.Nanoparticles: Boosting Efficacy of Drugs - Read more

COPD: The Mystery of The Third Signal

( Source: MEDICA.de )

Photo: Lung tissue [18/09/2012] At least three protective mechanisms defend the lungs against erroneous attacks by the body's own immune system. This was discovered by the Immuneregulation research group of Professor Dunja Bruder at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany.COPD: The Mystery of The Third Signal - Read more

T Cells in The Lung: License for Self-destruction

( Source: MEDICA.de )

Photo: Lung explant [07/09/2012] A research team of the University Medical Center Göttingen could now show that the Multiple Sclerosis-causing immune cells are programmed in the lung to be more motile and to efficiently break through blood vessel barriers.T Cells in The Lung: License for Self-destruction - Read more

Brain: Nanoparticles Reboot Blood Flow

( Source: MEDICA.de )

Photo: Traumatic brain-injury victim [27/08/2012] A nanoparticle developed at Rice University and tested in collaboration with Baylor College of Medicine (BCM) may bring great benefits to the emergency treatment of brain-injury victims, even those with mild injuries.Brain: Nanoparticles Reboot Blood Flow - Read more

Neurology: Video Shows The Traffic Inside a Brain Cell

( Source: MEDICA.de )

Photo: Screenshot of the video [24/08/2012] Using bioluminescent proteins from a jellyfish, a team of scientists has lit up the inside of a neuron, capturing spectacular video footage that shows the movement of proteins throughout the cell.Neurology: Video Shows The Traffic Inside a Brain Cell - Read more

Genotype: Acute Stress Alters Control of Gene Activity

( Source: MEDICA.de )

Picture: Drawing [15/08/2012] Acute stress alters the methylation of the DNA and thus the activity of certain genes. This is reported by researchers at the Ruhr-Universität Bochum, Germany, together with colleagues from Basel, Trier and London for the first time.Genotype: Acute Stress Alters Control of Gene Activity - Read more

Cancer Therapies: New Method May Allow Personalized Clinical Trial

( Source: MEDICA.de )

Photo: Woman on chemotherapy [14/08/2012] An approach, developed by investigators at Vanderbilt-Ingram Cancer Center, shows that erlotinib – a targeted therapy that acts on a growth factor receptor mutated in some lung, brain and other cancers – does not simply kill tumor cells as was previously assumed.Cancer Therapies: New Method May Allow Personalized Clinical Trial - Read more

Diabetes: White Blood Cells Mediate Insulin Resistance

( Source: MEDICA.de )

Photo: Neutrophil [07/08/2012] Researchers at the University of California, San Diego say neutrophils, an abundant type of white blood cell typically tasked with attacking bacteria and other foreign invaders, also plays an unexpected role in mediating insulin resistance – the central characteristic of type 2 diabetes, which afflicts an estimated 26 million Americans.Diabetes: White Blood Cells Mediate Insulin Resistance - Read more

Herpes: Virus Throws a Wrench in The Immune System

( Source: MEDICA.de )

Photo: Two T cells (red) [17/07/2012] The cytomegalovirus (CMV) is a member of the herpes virus family. Although most people carry CMV for life, it hardly ever makes them sick. Researchers from the Helmholtz Centre for Infection Research and from the USA have now unveiled long term consequences of the on-going presence of CMV.Herpes: Virus Throws a Wrench in The Immune System - Read more

Beating Heart: Trafficking of Immune Cells

( Source: MEDICA.de )

Photo: Image of a beating heart [16/07/2012] Now, working in mice, surgeons and scientists at Washington University School of Medicine in St. Louis, have captured the first images of a beating heart at a resolution so detailed they can track individual immune cells swarming into the heart muscle, causing inflammation.Beating Heart: Trafficking of Immune Cells - Read more

Switzerland: Recommendations of Federal Office of Public Health Reinforced

( Source: MEDICA.de )

Photo: Bonestructure [06/07/2012] Several clinical trials have looked at whether the number of hip fractures and the horrendous costs associated with them can be reduced by administering prophylactic vitamin D. The results have been inconsistent. Researchers working with Heike Bischoff-Ferrari from the Centre on Ageing and Mobility at Zurich University have now produced a new overview of the data. Switzerland: Recommendations of Federal Office of Public Health Reinforced - Read more

Nutrition: How Fat Regulates Cholesterol Absorption

( Source: MEDICA.de )

Photo: Zebrafish [28/06/2012] James Walters and his colleagues at the Carnegie Institution for Science are using zebrafish to better understand the cellular mechanisms of cholesterol processing and have discovered a surprising link between dietary fat and cholesterol absorption.Nutrition: How Fat Regulates Cholesterol Absorption - Read more

Bacteria: Following Oxygen

( Source: MEDICA.de )

Photo: Changes within HemAT [25/06/2012] How single cell organisms like bacteria manage to react to their environment is not yet completely understood. Together with colleagues from Japan, Doctor Samir El-Mashtoly from the Ruhr University Bochum, Germany, has gained new insights into the molecular interactions.Bacteria: Following Oxygen - Read more

Skin Cancer: Cause of Pain in the Treatment

( Source: MEDICA.de )

Photo: Experiment with red light [21/06/2012] Apply the ointment, light on, light off – that is how easy it is to cure various forms of non-melanoma skin cancer. However, the majority of patients suffer severe pain during the so-termed photodynamic therapy. Why the treatment can be so painful has now been uncovered.Skin Cancer: Cause of Pain in the Treatment - Read more

Bioinformatics: How Many Cells Can Our Blood Tolerate?

( Source: MEDICA.de )

Photo: Tweezers with blood [15/06/2012] Bioinformaticians of Jena University calculated the optimal value of hematocrit with the help of Einstein‘s equation.Bioinformatics: How Many Cells Can Our Blood Tolerate? - Read more

Systems Biology: "There is an enormous automation in laboratory techniques"

( Source: MEDICA.de )

[08/06/2012] The function of systems biology is to treat organs and biological organisms as a whole. In doing so, researchers among other things examine interactions and different aspects of the human cell. This still young discipline creates interfaces to biology, mathematics and physics to be able to understand regulatory processes for cells, tissues and organisms and thus get an integrated idea.Systems Biology: "There is an enormous automation in laboratory techniques" - Read more

Huntington's Disease: Cell Contents for Controlling Toxicity

( Source: MEDICA.de )

Photo: Cells [08/06/2012] New research into the cell-damaging effects of Huntington's disease suggests a potentially new approach for identifying possible therapeutic targets for treating the nerve-destroying disorder.Huntington's Disease: Cell Contents for Controlling Toxicity - Read more

Brain Cancer: Treating Drug-resistant Tumour Cells

( Source: MEDICA.de )

[05/06/2012] New research from the University of Wisconsin-Madison explains why the incurable brain cancer, glioblastoma multiforme (GBM), is highly resistant to current chemotherapies.Brain Cancer: Treating Drug-resistant Tumour Cells - Read more

From Stem Cell to Brain Cell: New Technique Mimics the Brain

( Source: MEDICA.de )

[24/05/2012] A new technique that converts stem cells into brain cells has been developed by researchers at Lund University. The method is simpler, quicker and safer than previous research has shown and opens the doors to a shorter route to clinical cell transplants.From Stem Cell to Brain Cell: New Technique Mimics the Brain - Read more

Microscope: Rainbow of Light to Image Blood Cells

( Source: MEDICA.de )

Photo: A single line within a blood vessel [22/05/2012] Blood tests convey vital medical information, but the sight of a needle often causes anxiety and results take time. A new device developed by a team of researchers in Israel, however, can reveal much the same information as a traditional blood test in real-time, simply by shining a light through the skin.Microscope: Rainbow of Light to Image Blood Cells - Read more

Nerve Cell Production: “We can convert skin cells into nerve cells more efficiently”

( Source: MEDICA.de )

[22/05/2012] Until now, curing neurological disorders has been a vision of the future. Scientists at the LIFE & BRAIN Centre in Bonn, Germany, however have come a bit closer to achieving this with a new procedure and are now able to convert skin cells into nerve cells.Nerve Cell Production: “We can convert skin cells into nerve cells more efficiently” - Read more

Quorum Sensing: Fighting Bacteria's Strength in Numbers

( Source: MEDICA.de )

[21/05/2012] Scientists at The University of Nottingham have opened the way for more accurate research into new ways to fight dangerous bacterial infections by proving a long-held theory about how bacteria communicate with each other.Quorum Sensing: Fighting Bacteria's Strength in Numbers - Read more

Cancer: Growth Regulator mTORC2 Linked to Diabetes

( Source: MEDICA.de )

Photo: mTORC2 in the liver [15/05/2012] Scientists of the University of Basel show how inhibition of the protein mTOR signalling can impair carbohydrate metabolism and potentially lead to diabetes.Cancer: Growth Regulator mTORC2 Linked to Diabetes - Read more

Nerve Fibres: Glial Cells Pass on Metabolites to Neurons

( Source: MEDICA.de )

Photo: Glial cells [11/05/2012] Klaus Armin and his research group from the Max Planck Institute of Experimental Medicine in Göttingen, Germany, have now discovered possible mechanisms by which these glial cells in the brain can support their associated axons and keep them alive in the long term.Nerve Fibres: Glial Cells Pass on Metabolites to Neurons - Read more

Drugs Ferry: ”We are not limited to one active ingredient group or one active ingredient“

( Source: MEDICA.de )

[08/05/2012] Drugs that treat brain diseases such as Alzheimer’s disease or multiple sclerosis are most effective directly where they are needed – in the brain. Unfortunately, it is difficult to develop drugs that are capable of getting there specifically, since the so-called blood-brain barrier prevents this from happening. However, now a team led by Doctor Heiko Manninga succeeded in doing precisely that. Drugs Ferry: ”We are not limited to one active ingredient group or one active ingredient“ - Read more

Brain: New Understanding of Alzheimer's Trigger

( Source: MEDICA.de )

[07/05/2012] A highly toxic beta-amyloid – a protein that exists in the brains of Alzheimer's disease victims – has been found to greatly increase the toxicity of other more common and less toxic beta-amyloids, serving as a possible "trigger" for the advent and development of Alzheimer's, researchers at the University of Virginia have discovered.Brain: New Understanding of Alzheimer's Trigger - Read more

Neurodegenerative Diseases: Glycogen Accumulation in Neurons Causes Brain Damage

( Source: MEDICA.de )

Photo: Microscope image [03/05/2012] Collaborative research by groups headed by scientists Joan J. Guinovart and Marco Milán at the Institute for Research in Biomedicine (IRB Barcelona) has revealed conclusive evidence about the harmful effects of the accumulation of glucose chains (glycogen) in fly and mouse neurons.Neurodegenerative Diseases: Glycogen Accumulation in Neurons Causes Brain Damage - Read more

Seeing: Foetal Membrane Transplantation Prevents Blindness

( Source: MEDICA.de )

[30/04/2012] Transplanting tissue from newborn foetal membranes prevents blindness in patients with a devastating disease called Stevens-Johnson syndrome, a Loyola University Medical Centre study has found.Seeing: Foetal Membrane Transplantation Prevents Blindness - Read more

Kras Gene: Pancreatic Tumours Depend on Oncogene Activity

( Source: MEDICA.de )

Photo: Pancreas [27/04/2012] Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice cannot survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells.Kras Gene: Pancreatic Tumours Depend on Oncogene Activity - Read more

Neurology: Brain-Machine Interface Moves a Paralysed Hand

( Source: MEDICA.de )

Photo: Brain [23/04/2012] A new Northwestern Medicine brain-machine technology delivers messages from the brain directly to the muscles - bypassing the spinal cord - to enable voluntary and complex movement of a paralysed hand. The device could eventually be tested on, and perhaps aid, paralysed patients.Neurology: Brain-Machine Interface Moves a Paralysed Hand - Read more

HIV-related Cancer Virus: New Trigger for Alternate Reproduction Pathway

( Source: MEDICA.de )

[19/04/2012] A research team led by Children’s National Medical Centre has identified a trigger that causes latent Kaposi’s sarcoma-associated herpes virus (KSHV) to rapidly replicate itself. KSHV causes Kaposi’s sarcoma, primary effusion lymphoma, and other cancers that commonly affect immunocompromised patients, including those with AIDS.HIV-related Cancer Virus: New Trigger for Alternate Reproduction Pathway - Read more

Viruses: Unexpected Partnership Drives Immunity

( Source: MEDICA.de )

Photo: Filters in the body’s drainage system [16/04/2012] New research of Harvard Medical School (HMS) challenges a well-established theory about antiviral immunity and may lead to a new understanding of the best way to help protect those exposed to potentially lethal viruses, such as rabies.Viruses: Unexpected Partnership Drives Immunity - Read more

Chromosome: Sequencing Technology Decodes DNA Folding Pattern

( Source: MEDICA.de )

Photo: DNA [12/04/2012] Using a powerful DNA sequencing methodology, researchers at the Ludwig Institute for Cancer Research have now investigated the three-dimensional structure of DNA folds in the nucleus of a chromosome. The findings provide scientists with a greater understanding about the basic principles of DNA folding and its role in gene regulation.Chromosome: Sequencing Technology Decodes DNA Folding Pattern - Read more

Proteins: Hot on the Trail of Metabolic Diseases and Resistance to Antibiotics

( Source: MEDICA.de )

Photo: Detailed side-view of “TM287/288” [29/03/2012] Proteins belonging to the large and important family of ABC transporters have been associated with metabolic diseases and can cause resistance to antibiotics. Biochemists from the University of Zurich have succeeded in determining the atomic structure of a new ABC transporter. The insights gained could give rise to new therapies to treat multi-resistant bacteria, cystic fibrosis or gout.Proteins: Hot on the Trail of Metabolic Diseases and Resistance to Antibiotics - Read more

Excess Insulin Levels: Unlikely Cause of Atherosclerosis

( Source: MEDICA.de )

[29/03/2012] A number of studies have shown that excess insulin circulating in the bloodstream is a major independent risk factor for cardiovascular disease. However, a new study from Joslin Diabetes Centre finds that this condition, called hyperinsulinemia, is itself not a cause of atherosclerosis.Excess Insulin Levels: Unlikely Cause of Atherosclerosis - Read more

CT Screening: Growth Rates of Lung Cancers Found

( Source: MEDICA.de )

Photo: Lung [27/03/2012] According to the latest report from the International Early Lung Cancer Action Program (I-ELCAP), lung cancers diagnosed in annual repeat rounds of CT screening are similar — both in volume doubling time and cell-type distribution — to those found in clinical practice.CT Screening: Growth Rates of Lung Cancers Found - Read more

Infections: Novel Pathway for T-cell Activation in Leprosy

( Source: MEDICA.de )

[27/03/2012] University of California – Los Angeles researchers pinpointed a new mechanism that potently activates T-cells, the group of white blood cells that play a major role in fighting infections. The team specifically studied how dendritic cells, immune cells located at the site of infection, become more specialised to fight the leprosy pathogen known as Mycobacterium leprae.Infections: Novel Pathway for T-cell Activation in Leprosy - Read more

Biomedicine: Somatic Stem Cells Obtained from Skin Cells

( Source: MEDICA.de )

Photo: Stem cells [23/03/2012] Breaking new ground, scientists at the Max Planck Institute for Molecular Biomedicine in Münster, Germany, have succeeded in obtaining somatic stem cells from fully differentiated somatic cells. Stem cell researcher Hans Schöler and his team took skin cells from mice and have managed to induce the cells' differentiation into neuronal somatic stem cells.Biomedicine: Somatic Stem Cells Obtained from Skin Cells - Read more

Rett Syndrome: Bone Marrow Transplant Arrests Symptoms

( Source: MEDICA.de )

[20/03/2012] The Organisation Rett Syndrome Research Trust describes the results of using bone marrow transplant (BMT) to replace faulty immune system cells in models of Rett Syndrome. The procedure arrested many severe symptoms of the childhood disorder, including abnormal breathing and movement, and significantly extended the lifespan of Rett mouse models.Rett Syndrome: Bone Marrow Transplant Arrests Symptoms - Read more

Cells: Influence of Nanoparticles on Nutrient Absorption

( Source: MEDICA.de )

Photo: Nanoparticles [09/03/2012] Nanoparticles are everywhere. From cosmetics and clothes, to soda and snacks. But as versatile as they are, nanoparticles also have a downside, say researchers at Binghamton University and Cornell University. These tiny particles, even in low doses, could have a big impact on our long-term health.Cells: Influence of Nanoparticles on Nutrient Absorption - Read more

T Lymphocytes: Tonsils Make T-Cells

( Source: MEDICA.de )

[07/03/2012] A new study provides evidence that a critical type of immune cell can develop in human tonsils. The cells, called T lymphocytes, or T cells, have been thought to develop only in the thymus, an organ of the immune system that sits on the heart.T Lymphocytes: Tonsils Make T-Cells - Read more

Autophagy: Protein Identified that Can Lengthen Our Life

( Source: MEDICA.de )

Photo: Cells [02/03/2012] Cells use various methods to break down and recycle worn-out components – autophagy is one of them. Karin Håberg of the Umeå University, Sweden, shows that the protein SNX18 is required for cells to be able to perform autophagy.Autophagy: Protein Identified that Can Lengthen Our Life - Read more

Neurodegenerative Disease: View on Causal Mechanism in ALS

( Source: MEDICA.de )

Photo: Microscopic image of a spinal cord section [01/03/2012] In a study Munich-based researchers refute a widely accepted hypothesis about a causative step in neurodegenerative conditions. These results deal specifically with animal models of human amyotrophic lateral sclerosis (ALS, aka Lou Gehrig's disease) but also raise questions for research on other neurodegenerative diseases, such as Alzheimer's or Huntington's disease.Neurodegenerative Disease: View on Causal Mechanism in ALS - Read more

Nerve Pathways: How the Brain Communicates

( Source: MEDICA.de )

Photo: Nerve cells [29/02/2012] An important mechanism by which the human brain hemispheres communicate with each other has been discovered by a team of researchers from Berlin and the University of Bern. The findings provide new insights into nerve cell communication in the brain that could also play a role in stroke.Nerve Pathways: How the Brain Communicates - Read more

Cancer: How to Rescue the Immune System

( Source: MEDICA.de )

[28/02/2012] In a study Loyola researchers report on a promising new technique that potentially could turn immune system killer T cells into more effective weapons against infections and possibly cancer.Cancer: How to Rescue the Immune System - Read more

Heart Attack: Injectable Gel Could Repair Tissue

( Source: MEDICA.de )

[24/02/2012] University of California, San Diego researchers have developed a new injectable hydrogel that could be an effective and safe treatment for tissue damage caused by heart attacks.Heart Attack: Injectable Gel Could Repair Tissue - Read more

From Nanosensors to Cytotoxicity Test: ”We can reduce the number of animal experiments“

( Source: MEDICA.de )

[22/02/2012] Animal experiments are a part of everyday life in medical research, yet they have been the subject of criticism for decades. Even though scientists all over the world are searching for alternative methods, the complexity of physical processes in the human body however makes this very difficult.From Nanosensors to Cytotoxicity Test: ”We can reduce the number of animal experiments“ - Read more

Obesity and Liver Disease: Faulty Fat Sensor Implicated

( Source: MEDICA.de )

[21/02/2012] Defects in a protein that functions as a dietary fat sensor may be a cause of obesity and liver disease, according to a study led by researchers at Imperial College London. The findings highlight a promising target for new drugs to treat obesity and metabolic disorders.Obesity and Liver Disease: Faulty Fat Sensor Implicated - Read more

Diabetic Patients: Pancreatic Hormone Linked with Severe Heart Disease in Obese

( Source: MEDICA.de )

Photo: Heart and stethoscope [17/02/2012] Severe heart damage in people who are obese and diabetic is linked with a pancreatic hormone called amylin, University of California Davis researchers have found. In the failing hearts of patients who were obese and diabetic, the scientists discovered strings of proteins, small fibres and plaques made of amylin, the hormone that produces the feeling of being full after eating.Diabetic Patients: Pancreatic Hormone Linked with Severe Heart Disease in Obese - Read more

Tumour: Antibodies to Intracellular Cancer Antigens Enhance Immunity

( Source: MEDICA.de )

Photo: Cancer patient and physician [15/02/2012] An international team of scientists in Japan, Switzerland, and the United States has confirmed that combining chemotherapy and immunotherapy in cancer treatment enhances the immune system's ability to find and eliminate cancer cells, even when the cancer-associated proteins targeted by the immune system are hidden behind the cancer cell membrane.Tumour: Antibodies to Intracellular Cancer Antigens Enhance Immunity - Read more

Neuron Memory: Key to Taming Chronic Pain

( Source: MEDICA.de )

[15/02/2012] A team of researchers led by McGill neuroscientist Terence Coderre, who is also affiliated with the Research Institute of the McGill University Health Centre, has found the key to understanding how memories of pain are stored in the brain. More importantly, the researchers are also able to suggest how these memories can be erased, making it possible to ease chronic pain.Neuron Memory: Key to Taming Chronic Pain - Read more

AIDS: Protein Protects Cells from HIV Infection

( Source: MEDICA.de )

Photo: HIV [13/02/2012] A novel discovery by researchers at New York University Langone Medical Centre and colleagues reveals a mechanism by which the immune system tries to halt the spread of HIV. Harnessing this mechanism may open up new paths for therapeutic research aimed at slowing the virus' progression to AIDS.AIDS: Protein Protects Cells from HIV Infection - Read more

Nerve Cells: Why the Middle Finger Has Such a Slow Connection

( Source: MEDICA.de )

Photo: Hand [07/02/2012] Each part of the body has its own nerve cell area in the brain –we therefore have a map of our bodies in our heads. The functional significance of these maps is largely unclear. What effects they can have is now shown by Ruhr-Universität Bochum, Germany, neuroscientists through reaction time measurements combined with learning experiments and “computational modelling”.Nerve Cells: Why the Middle Finger Has Such a Slow Connection - Read more

Cytoskeleton: Small Molecules at the Cell’s Membrane Enable Cell Movement

( Source: MEDICA.de )

Photo: Cells [03/02/2012] Cell biologists at Johns Hopkins have identified key steps in how certain molecules alter a cell’s skeletal shape and drive the cell’s movement. Results of their research have implications for figuring out what triggers the metastatic spread of cancer cells and wound-healing.Cytoskeleton: Small Molecules at the Cell’s Membrane Enable Cell Movement - Read more

Blood Cancer: Leukaemia Cells Are “Bad to the Bone”

( Source: MEDICA.de )

[30/01/2012] University of Rochester Medical Centre researchers have discovered new links between leukaemia cells and cells involved in bone formation, offering a fresh perspective on how the blood cancer progresses and raising the possibility that therapies for bone disorders could help in the treatment of leukaemia.Blood Cancer: Leukaemia Cells Are “Bad to the Bone” - Read more

Leukaemia: Drug Kills Cancerous T-Cells While Sparing Normal Immunity

( Source: MEDICA.de )

[26/01/2012] Leukemic cutaneous T-cell lymphoma (L-CTCL) is a leukaemia arising from T-cells, a type of white blood cell. This cancer can involve the skin and other organs, and patients often die within three years. Researchers of Brigham and Women's Hospital (BWH) report a new study that low-dose Campath not only treats patients with L-CTCL but does so without increasing their risk of infections.Leukaemia: Drug Kills Cancerous T-Cells While Sparing Normal Immunity - Read more

Cholesterol: Entry Point for Hepatitis C Infection Identified

( Source: MEDICA.de )

Photo: Liver [25/01/2012] A molecule embedded in the membrane of human liver cells that aids in cholesterol absorption also allows the entry of hepatitis C virus, the first step in hepatitis C infection, according to research at the University of Illinois at Chicago College of Medicine.Cholesterol: Entry Point for Hepatitis C Infection Identified - Read more

Dimethylsphingosine: New Understanding of Chronic Pain

( Source: MEDICA.de )

Photo: Man with pain [23/01/2012] Millions of people worldwide suffer from a type of chronic pain called neuropathic pain, which is triggered by nerve damage. Precisely how this pain persists has been a mystery, and current treatments are largely ineffective. But a team led by scientists from The Scripps Research Institute, using a new approach known as metabolomics, has now discovered a major clue: dimethylsphingosine (DMS).Dimethylsphingosine: New Understanding of Chronic Pain - Read more

Neural Balls and Strikes: Where Categories Live in the Brain

( Source: MEDICA.de )

Photo: Image of brain [18/01/2012] Hundreds of times during a baseball game, the home plate umpire must instantaneously categorise a fast-moving pitch as a ball or a strike. In new research from the University of Chicago, scientists have pinpointed an area in the brain where these kinds of visual categories are encoded.Neural Balls and Strikes: Where Categories Live in the Brain - Read more

T Cells Therapy: How Immune Cells Destroy Cancer Cells

( Source: MEDICA.de )

[17/01/2012] Doctor Kathleen Anders and Professor Thomas Blankenstein of the Max Delbrück Centre (MDC) Berlin-Buch and researchers of the Beckman Research Institute of the City of Hope Cancer Centre in Duarte, California, USA showed that drug-based cancer treatment and adoptive T cell therapy are both highly effective against large tumours.T Cells Therapy: How Immune Cells Destroy Cancer Cells - Read more

Drug Safety: Novel Way to Prevent Drug-Induced Liver Injury

( Source: MEDICA.de )

Photo: Mouse livers under microscopy [17/01/2012] Rutgers University and Massachusetts General Hospital (MGH) investigators have developed a novel strategy to protect the liver from drug-induced injury and improve associated drug safety.Drug Safety: Novel Way to Prevent Drug-Induced Liver Injury - Read more

Cryo-Electron Microscopy: Novel Approach to View Inner Workings of Viruses

( Source: MEDICA.de )

Photo: Cryo-electron micrographs of purified viruses [13/01/2012] Since the discovery of the microscope, scientists have tried to visualise smaller and smaller structures to provide insights into the inner workings of human cells, bacteria and viruses. Now, researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) have developed a new way to see structures within viruses that were not clearly seen before.Cryo-Electron Microscopy: Novel Approach to View Inner Workings of Viruses - Read more

Cirrhosis: High Rates of Disability and Health Care

( Source: MEDICA.de )

Photo: Patient [12/01/2012] Older patients with cirrhosis have significant functional disability, require twice the amount of informal care giving, and contribute added strain on the health care system, according to University of Michigan research. Given the increase in obesity and aging of those with hepatitis C (HCV), researchers expect the prevalence of cirrhosis to climb among older Americans.Cirrhosis: High Rates of Disability and Health Care - Read more

Prostate: New Strategy to Deliver Chemotherapy to Cancer Cells

( Source: MEDICA.de )

Photo: Prostate cancer cells [11/01/2012] Honing chemotherapy delivery to cancer cells is a challenge for many researchers. Getting the cancer cells to take the chemotherapy "bait" is a greater challenge. But perhaps such a challenge has not been met with greater success than by the nanotechnology research team of Brigham and Women's Hospital (BWH).Prostate: New Strategy to Deliver Chemotherapy to Cancer Cells - Read more

Mucopolysaccharidoses: New Test Spots Early Signs of Inherited Metabolic Disorders

( Source: MEDICA.de )

Photo: Blood cells [09/01/2012] A team of scientists, led by researchers at the University of California, San Diego School of Medicine, have developed a simple, reliable test for identifying biomarkers for mucopolysaccharidoses (MPS), a group of inherited metabolic disorders that are currently diagnosed in patients only after symptoms have become serious and the damage possibly irreversible.Mucopolysaccharidoses: New Test Spots Early Signs of Inherited Metabolic Disorders - Read more

Cholesterol: Benefits of Statin Therapy May Extend Beyond Lowering Lipids

( Source: MEDICA.de )

Graphik: Blood clot formation [05/01/2012] A study led by researchers from the University of North Carolina at Chapel Hill School of Medicine, has identified a molecular pathway that leads to this abnormal blood clotting and turned it off using a popular class of cholesterol-lowering drugs, statins.Cholesterol: Benefits of Statin Therapy May Extend Beyond Lowering Lipids - Read more

Drug Research: Fewer Animal Experiments Thanks to Nanosensors

( Source: MEDICA.de )

[04/01/2012] Experiments on animals have been the subject of criticism for decades. The number of tests involving laboratory animals has in fact gone up. Now, researchers of the Fraunhofer Research Institution for Modular Solid State Technologies EMFT in Munich, Germany have found an alternative approach: they hope sensor nanoparticles will reduce the need for animal testing.Drug Research: Fewer Animal Experiments Thanks to Nanosensors - Read more

Monkey pox: Novel Compound to Halt Virus Replication

( Source: MEDICA.de )

Photo: Man with pox [04/01/2012] Scientists of Boston University School of Medicine (BUSM) have identified a novel compound that inhibits viruses from replicating. The findings could lead to the development of highly targeted compounds to block the replication of poxviruses, such as the emerging infectious disease Monkey pox.Monkey pox: Novel Compound to Halt Virus Replication - Read more

Cells: Hepatitis C Virus Hijacks Liver MicroRNA

( Source: MEDICA.de )

[03/01/2012] Scientists at the University of North Carolina, working with colleagues from the University of Colorado, have shown for the first time how a small RNA molecule that regulates gene expression in human liver cells has been hijacked by the hepatitis C virus to ensure its own survival – helping medical scientists understand why a new antiviral drug appears to be effective against the virus.Cells: Hepatitis C Virus Hijacks Liver MicroRNA - Read more

Sensory Perception: Multisensory Integration - When Correlation Implies Causation

( Source: MEDICA.de )

Photo: Study participant during the experiment; verlinkt zu [16/12/2011] New research involving scientists from the Max Planck Institute for Biological Cybernetics, the Bernstein Center for Computational Neuroscience Tübingen (Germany), the University of Oxford, and the University of Bielefeld (Germany) has demonstrated that humans exploit the correlation between the temporal structures of signals to decide which of them to combine and which to keep segregated.Sensory Perception: Multisensory Integration - When Correlation Implies Causation - Read more

Statins: Cholesterol-Lowering Medication Accelerates Depletion of Plaque in Arteries

( Source: MEDICA.de )

Photo: Blood clots; linked to [15/12/2011] In a new study, NYU Langone Medical Centre researchers have discovered how cholesterol-lowering drugs called statins promote the breakdown of plaque in the arteries. The findings support a large clinical study that recently showed patients taking high-doses of the cholesterol-lowering medications not only reduced their cholesterol levels but also reduced the amount of plaque in their arteries.Statins: Cholesterol-Lowering Medication Accelerates Depletion of Plaque in Arteries - Read more

Cells: Protection Against Early Stages of Atherosclerosis

( Source: MEDICA.de )

[14/12/2011] Researchers from Boston University School of Medicine (BUSM) have identified for the first time the A2b adenosine receptor (A2bAR) as a possible new therapeutic target against atherosclerosis resulting from a diet high in fat and cholesterol. The findings may have significant public health implications.Cells: Protection Against Early Stages of Atherosclerosis - Read more

Control by the Matrix: Role of Proteins in the Cell Environment

( Source: MEDICA.de )

Photo: Precursor cell culture [14/12/2011] How astrocytes, certain cells of the nervous system, are generated was largely unknown up to now. Researchers of Ruhr-Universität Bochum (Germany) have now investigated what influence the cell environment, known as the extracellular matrix, has on this process.Control by the Matrix: Role of Proteins in the Cell Environment - Read more

Gene Therapy: Early Success Against Hereditary Bleeding Disorder

( Source: MEDICA.de )

[13/12/2011] Symptoms improved significantly in adults with the bleeding disorder haemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the United Kingdom.Gene Therapy: Early Success Against Hereditary Bleeding Disorder - Read more

Heart Attacks: Stopping Dangerous Cell Regrowth Reduces Risk

( Source: MEDICA.de )

[08/12/2011] Like Yin and Yang, the two proteins have opposite effects in the walls of blood vessels. AIF-1 stimulates undesirable formation of new cells after a vascular injury, and IRT-1 has the opposite effect. It is the latter, IRT-1, that researcher of Lund University in Sweden and Temple University in the USA want to use to stop a dangerous development in the artery.Heart Attacks: Stopping Dangerous Cell Regrowth Reduces Risk - Read more

Medaka Fish: An Eye on Stem Cells

( Source: MEDICA.de )

Photo: Retina of the medaka fish; linked to [06/12/2011] A single stem cell has the potential to generate offspring that differentiates into a variety of specialised cell types. This has now been shown by a team of biologists at the Heidelberg University (Germany) in the adult retina of the medaka fish as a model system.Medaka Fish: An Eye on Stem Cells - Read more

Brain: New Clues to Development of Autism

( Source: MEDICA.de )

[29/11/2011] Neuroscientists at Stanford University School of Medicine have homed in on potential differences in autistic people's brain cells by studying brain like spheres grown in an elaborate process from skin cells.Brain: New Clues to Development of Autism - Read more

Neurobiology: Researchers Decode a Puzzling Movement Disorder

( Source: MEDICA.de )

[28/11/2011] Neurodegenerative diseases represent one of the greatest challenges of our aging society. However, investigation into these diseases is made particularly difficult due to the limited availability of human brain tissue. Scientists from the Life and Brain Research Centre and Neurology Clinic of Bonn University (Germany) have now taken a roundabout path.Neurobiology: Researchers Decode a Puzzling Movement Disorder - Read more

Joint Disease: Better Dealing with Osteoarthritis

( Source: MEDICA.de )

[25/11/2011] A step towards better understanding of the biological mechanism involved in the onset of osteoarthritis (OA), which affects millions of people around the world, has been shown in research carried out at the Hebrew University of Jerusalem and in the United States.Joint Disease: Better Dealing with Osteoarthritis - Read more

Damaged Nerves: Improved Method of Electrical Stimulation Could Help Treat

( Source: MEDICA.de )

[24/11/2011] Earlier this fall, a plastic surgery research team at Beth Israel Deaconess Medical Centre (BIDMC) found a new method of nerve stimulation that reduces the device's electrical threshold by 40 per cent, compared with traditional FES therapy. The findings could help researchers develop a safer, more efficient functional electrical stimulation (FES) therapy with fewer side effects.Damaged Nerves: Improved Method of Electrical Stimulation Could Help Treat - Read more

Blood Vessels: Substance in Cancer Medicine Could Prevent Heart Attacks

( Source: MEDICA.de )

Photo: Patient with heart attack in emergency room; linked to [24/11/2011] A substance in medicines for cancer and epilepsy could also prevent heart attacks, according to researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, who have been using it to stimulate the body’s own defence system against blood clots.Blood Vessels: Substance in Cancer Medicine Could Prevent Heart Attacks - Read more

Cells: New Class of Drugs for the Reversible Inhibition of Proteasomes

( Source: MEDICA.de )

Photo: Hydroxyurea derivative blocks the proteasome; linked to [23/11/2011] As the “recycling plant” of the cell, the proteasome regulates vitally important functions. Cancer cells, in particular, are very sensitive because they need the proteasome for their uncontrolled growth. Biochemists at the Technische Universitaet Muenchen (TUM) have now identified the lead structure of a new class of drugs that attacks the proteasome in an unusual way.Cells: New Class of Drugs for the Reversible Inhibition of Proteasomes - Read more

Abdominal Cancers: Probiotic Protects Intestine from Radiation Injury

( Source: MEDICA.de )

[22/11/2011] Scientists at Washington University School of Medicine in St. Louis have shown that taking a probiotic before radiation therapy can protect the intestine from damage — at least in mice. The new study suggests that taking a probiotic also may help cancer patients avoid intestinal injury, a common problem in those receiving radiation therapy for abdominal cancers.Abdominal Cancers: Probiotic Protects Intestine from Radiation Injury - Read more

Haemoglobin: Protection from Severe Malaria Explained

( Source: MEDICA.de )

Photo: Blood cells with haemoglobin [22/11/2011] Why do people with a hereditary mutation of the red blood pigment haemoglobin (as is the case with sickle-cell anaemia prevalent in Africa) not contract severe malaria? Scientists in the group headed by Professor Michael Lanzer of the Department of Infectious Diseases at Heidelberg University Hospital (Germany) have now solved this mystery.Haemoglobin: Protection from Severe Malaria Explained - Read more

Neuropathic Pain: “Nerves cannot be compared with telephone wires“

( Source: MEDICA.de )

[22/11/2011] Chronic neuropathic pain has many reasons and is often poorly diagnosed - at the same time, the origin of the pain has not been fully understood. Therefore scientific pain research has been trying to analyse specific neuropathic pain for some time.Neuropathic Pain: “Nerves cannot be compared with telephone wires“ - Read more

Diabetes: Brain Plays Role in Regulating Blood Sugar

( Source: MEDICA.de )

[10/11/2011] Researchers at Albert Einstein College of Medicine of Yeshiva University have demonstrated for the first time that the brain is a key player in regulating glucose metabolism in humans. The findings suggest that drugs targeting the brain and central nervous system could be a novel approach to treating diabetes.Diabetes: Brain Plays Role in Regulating Blood Sugar - Read more

Epilepsy research in the brains of mice: “The cell activity can be modulated as desired“

( Source: MEDICA.de )

[08/11/2011] What exactly happens in the brain during an epileptic seizure? And can this knowledge help in finding better therapies for patients in the future? Epilepsy research in the brains of mice: “The cell activity can be modulated as desired“ - Read more

Tumour Cell Formation and Growth: Metabolic Protein Plays Unexpected Role

( Source: MEDICA.de )

Photo: Brain tumour; linked to [07/11/2011] The embryonic enzyme pyruvate kinase M2 (PKM2) has a well-established role in metabolism and is highly expressed in human cancers. Now, a team led by researchers at the University of Texas MD Anderson Cancer Centre reports that PKM2 has important non-metabolic functions in cancer formation.Tumour Cell Formation and Growth: Metabolic Protein Plays Unexpected Role - Read more

Pharmacology: Nano-Technology Makes Medicine Greener

( Source: MEDICA.de )

[07/11/2011] Researchers at the University of Copenhagen are behind the development of a new method that will make it possible to develop drugs faster and greener. This will lead to cheaper medicine for consumers.Pharmacology: Nano-Technology Makes Medicine Greener - Read more

Chronic Wounds: "Among experts we focus far too little on the basics"

( Source: MEDICA.de )

[02/11/2011] If a wound does not heal within four to twelve weeks after emergence, doctors call it a chronic wound. In many cases underlying diseases such as venous or vascular disease or diabetes mellitus are the cause. A successful therapy, however, still presents a challenge and requires an interdisciplinary cooperation.Chronic Wounds: "Among experts we focus far too little on the basics" - Read more

Human Genes: “Junk DNA” May Give Rise to Evolutionary Innovation

( Source: MEDICA.de )

Photo: Japanese freshwater fish Medaka; verlinkt zu [02/11/2011] The vast majority of the human genome consists of DNA without any apparent function, so-called “junk DNA”. A study of Heidelberg University's Centre for Organismal Studies now highlights this “dark matter” of the genome as a resource for evolutionary novelty.Human Genes: “Junk DNA” May Give Rise to Evolutionary Innovation - Read more

Early Detection of Disease: New Top-Down Strategy of Identifying Proteins

( Source: MEDICA.de )

Photo: Protein; linked to [31/10/2011] The human genome has been mapped. Now, it's on to proteins, a much more daunting task. There are 20,300 genes, but there are millions of distinct protein molecules in our bodies. Many of these hold keys to understanding disease and targeting treatment. A team led by Northwestern University has developed a new "top-down" method that can separate and identify thousands of protein molecules quickly.Early Detection of Disease: New Top-Down Strategy of Identifying Proteins - Read more

Cardiology: New Pathway Critical to Heart Arrhythmia

( Source: MEDICA.de )

Photo: Medical book and stethoscope; linked to [28/10/2011] University of Maryland School of Medicine researchers have uncovered a previously unknown molecular pathway that is critical to understanding cardiac arrhythmia and other heart muscle problems. Understanding the basic science of heart and muscle function could open the door to new treatments.Cardiology: New Pathway Critical to Heart Arrhythmia - Read more

Brain Damage in Newborns: Enzyme Controlling Cell Death

( Source: MEDICA.de )

Photo: Newborn; linked to [26/10/2011] Brain damage due to birth asphyxia – where the brain is starved of oxygen around the time of delivery – is normally treated by cooling the infant, but this only helps one baby in nine. New research from the Sahlgrenska Academy at the University of Gothenburg, Sweden, could now pave the way for new ways of treating brain damage in newborns.Brain Damage in Newborns: Enzyme Controlling Cell Death - Read more

Tropical Medicine: “You must not underestimate the capability of these viruses“

( Source: MEDICA.de )

[22/10/2011] Tropical diseases used to appear almost exclusively in remote countries – hence the name. The mosquito bite was annoying, but nevertheless harmless in European regions. But the flying pests keep spreading and spreading. And they carry tiny, but dangerous pathogens. Scientists now found out that these viruses are now settling down in Europe. They are called Sindbis, Batai or Usutu. Tropical Medicine: “You must not underestimate the capability of these viruses“ - Read more

Drug Delivery: Gene Therapy Without a Needle

( Source: MEDICA.de )

Photo: Doctor with a needle; linked to [19/10/2011] For the first time, researchers of Ohio State University have found a way to inject a precise dose of a gene therapy agent directly into a single living cell without a needle. The technique uses electricity to “shoot” bits of therapeutic bio molecules through a tiny channel and into a cell in a fraction of a second.Drug Delivery: Gene Therapy Without a Needle - Read more

Diabetes: Older Beta Cells Act Young Again

( Source: MEDICA.de )

Photo: Beta cells; linked to [14/10/2011] Now, long-time by Juvenile Diabetes Research Foundation International (JDRF)-funded researchers at Stanford University have identified a pathway responsible for the age-related decline, and have shown that they can tweak it to get older beta cells to act young again - and start dividing.Diabetes: Older Beta Cells Act Young Again - Read more

Birth: Battle Between the Placenta and Uterus Could Help Explain Preeclampsia

( Source: MEDICA.de )

Photo: Thropoblast and maternal cells; linked to [12/10/2011] A battle that brews in the mother's womb between the father's biological goal to produce the biggest, healthiest baby possible versus the mother's need to live through delivery might help explain preeclampsia, an often deadly disease of pregnancy. In a new study, Yale researchers describe the mechanism that keeps these conflicting goals in balance.Birth: Battle Between the Placenta and Uterus Could Help Explain Preeclampsia - Read more

Blood Vessel: Circadian Clock May Impact Organ Transplant Success

( Source: MEDICA.de )

Photo: Heart; linked to [05/10/2011] Health care providers assess blood and tissue type as well as organ size and health to enhance transplant success. New research indicates that checklist might also need to include the circadian clock.Blood Vessel: Circadian Clock May Impact Organ Transplant Success - Read more

Diabetes: Hormonal Role in Glucose and Fat Metabolism

( Source: MEDICA.de )

[04/10/2011] Hormone researchers at the University of Houston (UH) have their sights set on providing long-term treatment options for diabetes, obesity and cardiovascular diseases by better understanding estradiol, the most potent naturally occurring oestrogen.Diabetes: Hormonal Role in Glucose and Fat Metabolism - Read more

Manipulated Gatekeeper: How Viruses Find Their Way Into the Cell Nucleus

( Source: MEDICA.de )

Photo: Viruses; linked to [04/10/2011] Adenoviruses cause respiratory diseases and are more dangerous for humans than previously assumed. They manipulate gatekeeper molecules and infiltrate the cell nucleus with the aid of the host cell. A team of researchers have succeeded in demonstrating this mechanism in detail for the first time.Manipulated Gatekeeper: How Viruses Find Their Way Into the Cell Nucleus - Read more

Neurology: Researchers Discover Key to Survival of Brain Cells

( Source: MEDICA.de )

Photo: Brain; linked to [30/09/2011] Professor Nicolas G. Bazan and his colleagues of Louisiana State University Health Sciences Centre (LSUHSC) New Orleans have discovered how a key chemical neurotransmitter that interacts with two receptors in the brain promotes either normal function or a disease process - determining whether brain cells live or die.Neurology: Researchers Discover Key to Survival of Brain Cells - Read more

Blood-forming Stem Cells: Scientists Expand Bone Marrow-derived Stem Cells in Culture

( Source: MEDICA.de )

Photo: Stem Cells [20/09/2011] All stem cells share the capability to replenish themselves by undergoing self-renewal. So far, efforts to grow and expand scarce blood-forming stem cells in culture for therapeutic applications have been met with limited success. Researchers at the Stowers Institute for Medical Research now successfully expanded cultured hematopoietic stem cells to a hundredfold. Blood-forming Stem Cells: Scientists Expand Bone Marrow-derived Stem Cells in Culture - Read more

Cell Activity: GPS in the Head?

( Source: MEDICA.de )

[16/09/2011] Professor Motoharu Yoshida and colleagues from Boston University investigated how the rhythmic activity of nerve cells supports spatial navigation. The research scientists showed that cells in the entorhinal cortex, which is important for spatial navigation, oscillate with individual frequencies. These frequencies depend on the position of the cells within the entorhinal cortex.Cell Activity: GPS in the Head? - Read more

New Study: Uterine Stem Cells to Treat Diabetes

( Source: MEDICA.de )

Photo: Slide shows insulin producing stem cells [16/09/2011] Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells.New Study: Uterine Stem Cells to Treat Diabetes - Read more

Cells: Separating a Cancer Prevention Drug from Heart Disease Risk

( Source: MEDICA.de )

[15/09/2011] Several clinical studies have shown that taking the anti-inflammatory drug celecoxib can reduce the risk of developing polyps that lead to colon cancers, at the cost of increasing the risk of heart disease. Researchers at Winship Cancer Institute of Emory University have identified a way that celecoxib pushes cancer cells into suicide, separately from its known effects.Cells: Separating a Cancer Prevention Drug from Heart Disease Risk - Read more

Protein: New 'Bouncer' Molecule Halts Rheumatoid Arthritis

( Source: MEDICA.de )

[12/09/2011] Researchers at Northwestern University Feinberg School of Medicine have discovered why the immune cells of people with rheumatoid arthritis become hyperactive and attack the joints and bones. The immune cells have lost their bouncer, the burly protein that keeps them in line the same way a bouncer in a nightclub controls rowdy patrons.Protein: New 'Bouncer' Molecule Halts Rheumatoid Arthritis - Read more

EHEC: Researchers Investigate the Attachment of the Bacteria in Detail

( Source: MEDICA.de )

Photo: EHEC-bacteria; linked to [08/09/2011] Scientists from the Helmholtz Centre for Infection Research (Helmholtz-Zentrum für Infektionsforschung, HZI) in Braunschweig, Germany, have now in cooperation with German and American colleagues uncovered new details of how canonical "entero-hemorrhagic Escherichia coli" bacteria (EHEC), serotype O157:H7, attach to intestinal cells. They deciphered at the atomic level how this binding works.EHEC: Researchers Investigate the Attachment of the Bacteria in Detail - Read more

Leukaemia: Researchers Found Mechanism That Can Help Design Future Therapies

( Source: MEDICA.de )

Photo: Graphic of blood cells; linked to [06/09/2011] An international team of researchers has found a group of mutations involved in T-cell acute lymphoblastic leukaemia (T-ALL), and showed that certain drugs, already in clinical use to treat other diseases, can eliminate the cells carrying these mutations.Leukaemia: Researchers Found Mechanism That Can Help Design Future Therapies - Read more

Immune System: Endogenous Approach to the Prevention of Allergies

( Source: MEDICA.de )

[05/09/2011] Universitätsmedizin Berlin and the Johannes Gutenberg University in Mainz have clarified an endogenous mechanism that can prevent the development of allergies. They were able to show that certain cells of the immune system, so-called killer dendritic cells, are capable of eliminating allergy cells. The results of the study open up new perspectives for strategies to protect against allergies.Immune System: Endogenous Approach to the Prevention of Allergies - Read more

Neurology: New Insight into Impulse Control

( Source: MEDICA.de )

Photo: Graphic of impulse; linked to [05/09/2011] How the brain controls impulsive behavior may be significantly different than psychologists have thought for the last 40 years. That is the unexpected conclusion of a study by an international team of neuroscientists.Neurology: New Insight into Impulse Control - Read more

Research: New Way to Target Shape-shifting Proteins

( Source: MEDICA.de )

Photo: Stripes of light [01/09/2011] A molecule which can stop the formation of long protein strands, known as amyloid fibrils, that cause joint pain in kidney dialysis patients has been identified by researchers at the University of Leeds. Research: New Way to Target Shape-shifting Proteins - Read more

Nano-thermometers: Differences in First Temperature Response within Living Cells Shown

( Source: MEDICA.de )

[31/08/2011] Using a modern version of open-wide-and-keep-this-under-your-tongue, scientists today reported taking the temperature of individual cells in the human body, and finding for the first time that temperatures inside do not adhere to the familiar 98.6 degree Fahrenheit norm.Nano-thermometers: Differences in First Temperature Response within Living Cells Shown - Read more

Like in Real Estates: In Cell Culture, the Neighbourhood Matters

( Source: MEDICA.de )

Photo: A Neighbourhood [30/08/2011] Ever since scientists first began growing human cells in lab dishes, they have focused on improving the chemical soup that feeds the cells and helps regulate their growth. But surfaces also matter, says Laura Kiessling, a professor of chemistry at the University of Wisconsin-Madison. Like in Real Estates: In Cell Culture, the Neighbourhood Matters - Read more

Study: New Target for Treatment of Type 2 Diabetes and Prediabetes

( Source: MEDICA.de )

Photo: Chocolate Mushmallow [25/08/2011] Researchers at the Joslin Diabetes Center have shown that an enzyme found in the mitochondria of cells is decreased in the skeletal muscle of those with diabetes, a finding that could lead to the development of drugs to boost the activity of this enzyme in an effort to fight the disease.Study: New Target for Treatment of Type 2 Diabetes and Prediabetes - Read more

Pandemics: Children's Hospitals Are Not Equipped

( Source: MEDICA.de )

Photo: A child in a hospital [24/08/2011] A new study of children's hospitals nationwide has found them underequipped to handle a major surge of patients in the event of a pandemic, and urges health care institutions and government agencies to immediately review emergency preparedness plans as flu season approaches.Pandemics: Children's Hospitals Are Not Equipped - Read more

Studies: Treatments for Breast and Colon Cancers

( Source: MEDICA.de )

[24/08/2011] University of Houston (UH) researchers have their sights set on developing possible treatments for breast and colon cancer. In two separate, yet related, studies professor Cecilia Williams and her team at the Center for Nuclear Receptors and Cell Signaling (CNRCS) explored the role of estrogen hormones in potentially treating and preventing these cancers.Studies: Treatments for Breast and Colon Cancers - Read more

Nitric Oxide: Newly Discovered Cell Mechanism to Fight C. Diff

( Source: MEDICA.de )

[23/08/2011] Groundbreaking research encompassing Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, has uncovered a natural defense mechanism that is capable of inactivating the toxin that spreads Clostridium difficile (C. diff) an increasingly common bacterial infection in hospitals and long-term care settings. Nitric Oxide: Newly Discovered Cell Mechanism to Fight C. Diff - Read more

Study: New Risk Score Spots Patients at High Risk of Serious Blood Clots

( Source: MEDICA.de )

Photo: Microscopic picture of blood [18/08/2011] A new risk prediction tool can identify patients at high risk of serious blood clots who might need preventative treatment. The tool is based on simple variables which the patient is likely to know and could be easily integrated into GP computer systems to risk assess patients prior to hospital admission, long haul flights, or starting medications that carry an increased clotting risk.Study: New Risk Score Spots Patients at High Risk of Serious Blood Clots - Read more

Proteins: Improved Method Holds Promise for Biomedical Research

( Source: MEDICA.de )

Photo: Microscopic picture of two peptide [17/08/2011] Antibodies are the backbone of the immune system—capable of targeting proteins associated with infection and disease. They are also vital tools for biomedical research, the development of diagnostic tests and for new therapeutic remedies.Proteins: Improved Method Holds Promise for Biomedical Research - Read more

Identification: Molecular Pathway Leads to Inflammation in Asthma

( Source: MEDICA.de )

[12/08/2011] Researchers at the University of Pittsburgh have identified a molecular pathway that helps explain how an enzyme elevated in asthma patients can lead to increased mucus production and inflammation that is characteristic of the lung condition. Their findings reveal unique interactions between biological molecules that could be targeted to develop new asthma treatments.Identification: Molecular Pathway Leads to Inflammation in Asthma - Read more

DNA: How Yeast Chromosomes Avoid the Bad Breaks

( Source: MEDICA.de )

[10/08/2011] During meiosis—the cell division that produces sperm and eggs—repetitive elements place the genome at risk for dangerous rearrangements from genome reshuffling. This recombination typically does not occur in repetitive DNA, in part because much of it is assembled into specialised heterochromatin. Other mechanisms that restrain recombination in repetitive DNA have remained elusive, until now.DNA: How Yeast Chromosomes Avoid the Bad Breaks - Read more

Discovery: Natural Food Preservative That Kills Food-Borne Bacteria

( Source: MEDICA.de )

[09/08/2011] University of Minnesota researchers have discovered and received a patent for a naturally occurring lantibiotic — a peptide produced by a harmless bacteria — that could be added to food to kill harmful bacteria like salmonella, E. coli and listeria.Discovery: Natural Food Preservative That Kills Food-Borne Bacteria - Read more

Small Molecules Hit It Big: New Therapeutic Approaches Against Viruses, Bacteria and Cancer

( Source: MEDICA.de )

Photo: Plan of molecules [09/08/2011] Scientists from Freie Universität Berlin and the NeuroCure Cluster of Excellence in collaboration with colleagues from Australia and the Leibniz Institute for Molecular Pharmacology (FMP) in Berlin have developed small molecules that inhibit the internalisation of important signaling molecules but also of pathogenic organisms such as the immunodeficiency virus (HIV) and bacteria into cells. Small Molecules Hit It Big: New Therapeutic Approaches Against Viruses, Bacteria and Cancer - Read more

New Therapy: Own Skin Cells May Treat Multiple Diseases

( Source: MEDICA.de )

Photo: Photo of a slide under a microscope [08/08/2011] The possibility of developing stem cells from a patient's own skin and using them to treat conditions as diverse as Parkinson's disease, Alzheimer's disease and cancer has generated tremendous excitement in the stem cell research community in recent years. Such therapies would avoid the controversial need for using stem cells derived from human embryos.New Therapy: Own Skin Cells May Treat Multiple Diseases - Read more

B Cells: Why Women Suffer More Autoimmune Disease

( Source: MEDICA.de )

[08/08/2011] Researchers at National Jewish Health have discovered a type of cell that may contribute to autoimmune disease. The findings also suggest why diseases such as lupus, multiple sclerosis and rheumatoid arthritis strike women more frequently than men.B Cells: Why Women Suffer More Autoimmune Disease - Read more

'Swamp Gas': Protecting Blood Vessels from Complications of Diabetes

( Source: MEDICA.de )

Photo: blood vessel [05/08/2011] Hydrogen sulfide is a foul-smelling gas with an odor resembling that of rotten eggs. Sometimes called "swamp gas," this toxic substance is generally associated with decaying vegetation, sewers and noxious industrial emissions. And — as odd as it may seem — it also plays a critical role in protecting blood vessels from the complications of diabetes, according to a new study. 'Swamp Gas': Protecting Blood Vessels from Complications of Diabetes - Read more

Cell Power: Mitochondrial Genome Mutates When Reprogrammed

( Source: MEDICA.de )

Photo: Chart with information of the experiment [04/08/2011] Induced pluripotent stem cells (iPS cells) can be generated individually for every single person. iPS cells can be generated from adult body cells using the technique of “cellular reprogramming”. The method raises no ethical concerns as it does not involve the destruction of embryos.Cell Power: Mitochondrial Genome Mutates When Reprogrammed - Read more

Radiology: Safety Checks Could Reduce Radiotherapy Errors

( Source: MEDICA.de )

[04/08/2011] A combination of several well-known safety procedures could greatly reduce patient-harming errors in the use of radiation to treat cancer, according to a new study led by Johns Hopkins researchers.Radiology: Safety Checks Could Reduce Radiotherapy Errors - Read more

Analysis: New Light on the Mechanisms of Brain Development

( Source: MEDICA.de )

Photo: Picture of  human brain [03/08/2011] Scientists at the Allen Institute for Brain Science have taken an important step in identifying how the brain organizes itself during development. The findings describe – in more detail than ever before – the consequences of the loss of a key molecule involved in establishing proper brain architecture during brain development.Analysis: New Light on the Mechanisms of Brain Development - Read more

Mechanism: Cell Position in the Intestinal Epithelium

( Source: MEDICA.de )

[02/08/2011] How do cells know where to position themselves and where to accumulate in order to carry out their functions correctly within each organ? Researchers have revealed the molecular mechanisms responsible for organizing the intestinal epithelium into distinct comportments, defined by frontiers or territories. Mechanism: Cell Position in the Intestinal Epithelium - Read more

Cancer: Introducing Maspin Protein into Tumor Nucleus Can Stop Growth

( Source: MEDICA.de )

Photo: Photo of a tumor [01/08/2011] According to the Canadian Cancer Society, one in four Canadians will die of cancer. Lawson Health Research Institute's Doctor John Lewis, Doctor Ann Chambers, and colleagues have found new hope for survival. Their new study shows that maspin, a cellular protein, can reduce the growth and spread of cancer cells - but only when it is in the nucleus.Cancer: Introducing Maspin Protein into Tumor Nucleus Can Stop Growth - Read more

Hope: Reprogrammed Kidney Cells Could Cure Kidney Disease

( Source: MEDICA.de )

Photo: Futuristic image of human kidney [28/07/2011] Approximately 60 million people across the globe have chronic kidney disease, and many will need dialysis or a transplant. A new research indicates that patients' own kidney cells can be gathered and reprogrammed. Reprogramming patients' kidney cells could mean that in the future, fewer patients with kidney disease would require complicated, expensive procedures that affect their quality of life.Hope: Reprogrammed Kidney Cells Could Cure Kidney Disease - Read more

Pituitary Cells: Unexpected Discovery on Hormone Secretion

( Source: MEDICA.de )

[28/07/2011] A team of geneticists at the Institut de recherches cliniques de Montréal (IRCM), directed by Doctor Jacques Drouin, made an unexpected discovery on hormone secretion. Contrary to common belief, the researchers found that pituitary cells are organized in structured networks. Pituitary Cells: Unexpected Discovery on Hormone Secretion - Read more

Neurology: Fast Prediction of Axon Behaviour

( Source: MEDICA.de )

[26/07/2011] Researchers at Case Western Reserve University have developed a computer modeling method to accurately predict how a peripheral nerve axon responds to electrical stimuli, slashing the complex work from an inhibitory weeks-long process to just a few seconds.Neurology: Fast Prediction of Axon Behaviour - Read more

Program: Software Helps Customize Protein Production

( Source: MEDICA.de )

Photo: Image of molecules [22/07/2011] A software program developed by a Penn State synthetic biologist could provide biotechnology companies with genetic plans to help them turn bacteria into molecular factories, capable of producing everything from biofuels to medicine.Program: Software Helps Customize Protein Production - Read more

Chromosomes: ‘Cord-stopper’ Protein Complex Makes Easier to Move

( Source: MEDICA.de )

Photo: Picture with protein complex [20/07/2011] In a study scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered how a protein complex called condensin keeps chromosome arms folded and easy-to-transport, potentially acting as a cord-stopper.Chromosomes: ‘Cord-stopper’ Protein Complex Makes Easier to Move - Read more

Identified: Regulator of Aggressive Breast Cancer

( Source: MEDICA.de )

[04/07/2011] Researchers at Cold Spring Harbor Laboratory (CSHL) have identified an enzyme that appears to be a significant regulator of breast cancer development. Called PTPN23, the enzyme is a member of a family called protein tyrosine phosphatases, or PTPs, that plays a fundamental role in switching cell signaling on and off.Identified: Regulator of Aggressive Breast Cancer - Read more

Chemotherapy: Bladder Cancer Cells More Susceptible

( Source: MEDICA.de )

[01/07/2011] Researchers at the UC Davis Cancer Center have discovered a way of sensitizing muscle-invasive bladder cancer cells so that they succumb to the toxic effects of chemotherapy. The finding adds to mounting evidence that tiny strands of RNA — called microRNA — play key roles in some of the deadliest types of cancer.Chemotherapy: Bladder Cancer Cells More Susceptible - Read more

Genetic “Conductor”: New Brain Cell Production in Adults

( Source: MEDICA.de )

Photo: Image of human head [01/07/2011] A team of North Carolina State University researchers has discovered more about how a gene connected to the production of new brain cells in adults does its job. Their findings could pave the way to new therapies for brain injury or disease.Genetic “Conductor”: New Brain Cell Production in Adults - Read more

New Tasks: Aurora Proteins in Cell Division

( Source: MEDICA.de )

Photo: Fission yeast under microscope [29/06/2011] When a cell divides, the genetic information in the chromosomes must be passed on error-free to the daughter cells. Researchers at the Friedrich Miescher Laboratory in Tübingen are studying this process using fission yeast as a model organism. New Tasks: Aurora Proteins in Cell Division - Read more

Skin Cells: New Molecular Pathway Involved in Wound-Healing

( Source: MEDICA.de )

[29/06/2011] Scientists from The Scripps Research Institute have identified a surprising new molecular pathway in skin cells that is involved in wound-healing and sensory communication.Skin Cells: New Molecular Pathway Involved in Wound-Healing - Read more

Cell cultivation: “You might describe it as gymnastics for cells“

( Source: MEDICA.de )

[22/06/2011] The cells of our body work within a three-dimensional environment. But under laboratory conditions, experiments are often still performed in Petri dishes, which provide a 2D environment. Cell cultivation: “You might describe it as gymnastics for cells“ - Read more

New Technique: Skin Cells Converted Into Brain Cells

( Source: MEDICA.de )

Photo: Portrayal of human brain [14/06/2011] A research has proven that it is possible to reprogram mature cells from human skin directly into brain cells, without passing through the stem cell stage. The unexpectedly simple technique involves activating three genes in the skin cells; genes which are already known to be active in the formation of brain cells at the foetal stage.New Technique: Skin Cells Converted Into Brain Cells - Read more

Neuronal Injury: Eating a High-Fat Diet May Rapidly Injure Brain Cells

( Source: MEDICA.de )

[09/06/2011] Obesity among people who eat a high-fat diet may involve injury to neurons, or nerve cells, in a key part of the brain that controls body weight, according to the authors of a new animal study. Neuronal Injury: Eating a High-Fat Diet May Rapidly Injure Brain Cells - Read more

Super Microscope: To Pinpoint Body’s Immunity 'Switch'

( Source: MEDICA.de )

[07/06/2011] Using the only microscope of its kind in Australia, medical scientists have been able for the first time to see the inner workings of T-cells, the front-line troops that alert our immune system to go on the defensive against germs and other invaders in our bloodstream.Super Microscope: To Pinpoint Body’s Immunity 'Switch' - Read more

Novel Pathway: Regulating Angiogenesis May Fight Retinal Disease

( Source: MEDICA.de )

Photo: Photo of blood cells [31/05/2011] Scientists identify a new molecular pathway used to suppress blood vessel branching in the developing retina – a finding with potential therapeutic value for fighting diseases of the retina and a variety of cancers.Novel Pathway: Regulating Angiogenesis May Fight Retinal Disease - Read more

Stem Cell Pluripotency: Researchers Discover Key Molecule

( Source: MEDICA.de )

Photo: Illustration of a molecule [30/05/2011] Researchers have discovered what enables embryonic stem cells to differentiate into diverse cell types and thus to be pluripotent. This pluripotency depends on a specific molecule – E-cadherin – hitherto primarily known for its role in mediating cell-cell adhesion as a kind of “intracellular glue”. If E-cadherin is absent, the stem cells lose their pluripotency. Stem Cell Pluripotency: Researchers Discover Key Molecule - Read more

Cellular Migration: Dance as a Minuet or a Mosh?

( Source: MEDICA.de )

Photo: Blood cells [23/05/2011] The physical forces that guide how cells migrate—how they manage to get from place to place in a coordinated fashion inside the living body— are poorly understood. Scientists have, for the first time, devised a way to measure these forces during collective cellular migration. Cellular Migration: Dance as a Minuet or a Mosh? - Read more

Identification: A Key to Fight Drug-Resistant Leukemia

( Source: MEDICA.de )

Photo: Leukemia cells [20/05/2011] An international team led by researchers at the University of California, San Francisco and joined by scientists of the Freiburg excellence cluster BIOSS – Centre for Biological Signalling Studies, has now identified a protein called BCL6 which plays a key role in the development of drug-resistance in leukemia. Identification: A Key to Fight Drug-Resistant Leukemia - Read more

Malaria: Risk Reduced by Genetic Predisposition for Cell Suicide

( Source: MEDICA.de )

[20/05/2011] A human genetic variant associated with an almost 30 percent reduced risk of developing severe malaria has been identified. Scientists reveal that a variant at the FAS locus can prevent an excessive and potentially hazardous immune response in infected children. Malaria: Risk Reduced by Genetic Predisposition for Cell Suicide - Read more

Lung Cells: Carbon Black Nanoparticles Can Cause Cell Death

( Source: MEDICA.de )

[19/05/2011] Researchers have found that inhaled carbon black nanoparticles create a double source of inflammation in the lungs.Lung Cells: Carbon Black Nanoparticles Can Cause Cell Death - Read more

New Way: Breast Cancer Cells Adapt to Environmental Stress

( Source: MEDICA.de )

Photo: Breast cancer check [17/05/2011] An international research team has discovered a new aspect of “metabolic transformation”, the process whereby tumour cells adapt and survive under conditions that would kill normal cells.New Way: Breast Cancer Cells Adapt to Environmental Stress - Read more

Heart Cell Signals: Discovery of Faint “Quark” Workings

( Source: MEDICA.de )

Photo: Subtle calcium release events [13/05/2011] Three years of microscopic experiments on heart cells has led to a discovery by a team of University of Maryland researchers and collaborators of the workings of faint calcium signals in the heart cells, a discovery that may translate into new therapies for heart disease. Heart Cell Signals: Discovery of Faint “Quark” Workings - Read more

Brain Research: Thinking Outside the Column

( Source: MEDICA.de )

Photo: A nerve cell cortex [02/05/2011] For more than 50 years, a dominating assumption in brain research was that nerve cells in the cortex of the brain are organised in the form of microscopically small columns. Subsequently, it became a textbook standard that connections are created predominantly between nerve cells within these columns. Brain Research: Thinking Outside the Column - Read more

Dyshidrosis: “A diagnosis and classification is still difficult“

( Source: MEDICA.de )

[02/05/2011] Multifaceted clinical patterns hide behind skin blistering. The different types of skin rashes can be caused by infections, allergies as well as internal diseases and are often beyond a reliable diagnosis. Dyshidrosis: “A diagnosis and classification is still difficult“ - Read more

Key Players: Cancer Cells' Survival Kit

( Source: MEDICA.de )

Photo: Cancer [27/04/2011] Scientists have discovered new details of how cancer cells escape from tumor suppression mechanisms that normally prevent these damaged cells from multiplying. They also demonstrated a potential link between this cell proliferation control mechanism and the cognitive deficits caused by Down syndrome.Key Players: Cancer Cells' Survival Kit - Read more

Immune Attack: GM-CSF Required in Multiple Sclerosis

( Source: MEDICA.de )

Foto: Man in a wheelchair before stairs [26/04/2011] The neutralization of the cytokine GM-CSF could halt the development of multiple sclerosis. This was demonstrated by the research team at the University of Zurich in an animal model. Immune Attack: GM-CSF Required in Multiple Sclerosis - Read more

Stress Response Mechanism: Call of the Riled

( Source: MEDICA.de )

[05/04/2011] Researchers say a "stress response" mechanism used by normal cells to cope with harsh or demanding conditions is exploited by cancer cells, which transmit the same stress signal to surrounding cells, triggering an inflammatory response in them that can aid tumor growth.Stress Response Mechanism: Call of the Riled - Read more

Mice: Nurturing Newborn Neurons Sharpens Mind

( Source: MEDICA.de )

Photo: Newborn Neurons in Mice [04/04/2011] Researchers, for the first time, pinpointed the effects of enhanced adult neurogenesis by creating mice lacking a gene required for programmed cell death of newborn neurons in the adult hippocampus. Mice: Nurturing Newborn Neurons Sharpens Mind - Read more

Genetic Conspirators: Development of Acute Myeloid Leukaemia

( Source: MEDICA.de )

[28/03/2011] Researchers have described how the most common gene mutation found in acute myeloid leukaemia starts the process of cancer development and how it can cooperate with a well-defined group of other mutations to cause full-blown leukaemia.Genetic Conspirators: Development of Acute Myeloid Leukaemia - Read more

Stem Cells: Promise for People With Rapidly Progressing MS

( Source: MEDICA.de )

Photo: stem cell [22/03/2011] A long term study reports about the effectiveness of replacing bone marrow, purposely destroyed by chemotherapy, with autologous (self) stem cell rescue for people with aggressive forms of multiple sclerosis. Stem Cells: Promise for People With Rapidly Progressing MS - Read more

Selective Control: Anxiety Pathways in the Brain

( Source: MEDICA.de )

Anxiety Pathways in the Brain [10/03/2011] Scientists at Stanford University recently used light to activate mouse neurons and precisely identify neural circuits that increase or decrease anxiety-related behaviors. Selective Control: Anxiety Pathways in the Brain - Read more

ADAM-12: Gene Could Hold Key to Cancer

( Source: MEDICA.de )

[09/03/2011] ADAM-12 is the name of a gene that researchers believe could be an important element in the fight against cancer, arthritis, and cardiac hypertrophy, or thickening of the heart's walls. ADAM-12: Gene Could Hold Key to Cancer - Read more

Uncovering: How Ovarian Cancer Resists Chemotherapy

( Source: MEDICA.de )

[04/03/2011] Researchers in the university's Faculty of Science & Engineering studied a tiny strand of our genetic makeup known as a MicroRNA, involved in the regulation of gene expression. Cancer occurs when gene regulation goes haywire. Uncovering: How Ovarian Cancer Resists Chemotherapy - Read more

HIV: Protein May Help the Virus's Resurgence

( Source: MEDICA.de )

Protein May Help the Virus's Resurgence [28/02/2011] New research enhances the current knowledge of how human immunodeficiency virus type-1 (HIV-1), which causes AIDS, controls the cell cycle of cells that it infects. The new findings may shed light on how the virus reactivates after entering a dormant state, called latency. HIV: Protein May Help the Virus's Resurgence - Read more

Full Film Frame: Family of Proteins Essential for Cell Function

( Source: MEDICA.de )

Family of Proteins Essential for Cell Function [24/02/2011] Researchers have completed the 3D structural sequence adopted by several essential proteins in the exchange of substances between the extra and intracellular milieu.Full Film Frame: Family of Proteins Essential for Cell Function - Read more

Personalised Medicine: Strategy for Identifying Biomarkers

( Source: MEDICA.de )

[18/02/2011] A team of biologists, clinical oncologists, pathologists and information scientists has established a strategy for identifying biomarkers. If a particular pattern of these biomarkers can be detected in the blood, this indicates a cancerous disease. Personalised Medicine: Strategy for Identifying Biomarkers - Read more

Parkinson's Disease: Problems with Mitochondria

( Source: MEDICA.de )

Problems with Mitochondria [17/02/2011] For the last several years, neurologists have been probing a connection between Parkinson's disease and problems with mitochondria, the miniature power plants of the cell. Parkinson's Disease: Problems with Mitochondria - Read more

Living in the Matrix: Sugar Residues Regulate Growth and Survival of Nerve Cells

( Source: MEDICA.de )

Sugar Residues Regulate Growth and Survival of Nerve Cells [15/02/2011] Researchers in Bochum have found out that certain sugar residues in the spinal cord regulate the growth and survival of nerve cells which control the movement of muscles. Living in the Matrix: Sugar Residues Regulate Growth and Survival of Nerve Cells - Read more

T Cells: How The Immune System is Regulated

( Source: MEDICA.de )

How The Immune System is Regulated [07/02/2011] Asthma, diabetes, rheumatism: Such diseases can arise when the immune system does not work properly. Researchers from the Universities of Würzburg and Mainz have discovered new findings about the regulation of the immune defense.T Cells: How The Immune System is Regulated - Read more

MicroRNA: Cocktail Helps Turn Skin Cells into Stem Cells

( Source: MEDICA.de )

Cocktail Helps Turn Skin Cells into Stem Cells [04/02/2011] Stem cells are ideal tools to understand disease and develop new treatments; however, they can be difficult to obtain in necessary quantities. MicroRNA: Cocktail Helps Turn Skin Cells into Stem Cells - Read more

Magnetic Stimulation: Brain Nerve Cells Can Be Influenced

( Source: MEDICA.de )

Brain Nerve Cells Can Be Influenced [28/01/2011] What sounds like science fiction is actually possible: thanks to magnetic stimulation, the activity of certain brain nerve cells can be deliberately influenced. What happens in the brain in this context has been unclear up to now. Magnetic Stimulation: Brain Nerve Cells Can Be Influenced - Read more

Safety Concerns: Experimental Cancer Approach

( Source: MEDICA.de )

Experimental Cancer Approach [26/01/2011] The strategy takes aim at a key signaling pathway, called Notch, involved in forming new blood vessels that feed tumor growth. When researchers targeted the Notch1 signaling pathway in mice, the animals developed vascular tumors, primarily in the liver, which led to massive hemorrhages that caused their death.Safety Concerns: Experimental Cancer Approach - Read more

Under Control: Reactivating Cancer Suppressor Genes

( Source: MEDICA.de )

Reactivating Cancer Suppressor Genes [19/01/2011] Scientists have brought cancer cells back under normal control — by reactivating their cancer suppressor genes. The discovery could form a powerful new technology platform for the treatment of cancer of the breast and other cancers. Under Control: Reactivating Cancer Suppressor Genes - Read more

Rare Genetic Disease: Skin Provides Australia’s First Adult Stem Cells

( Source: MEDICA.de )

[14/01/2011] Scientists have developed Australia’s first adult induced pluripotent stem cell lines using skin biopsies from patients with the rare genetic disease Friedreich Ataxia (FA).Rare Genetic Disease: Skin Provides Australia’s First Adult Stem Cells - Read more

Analysis of Medical Database: New Markers for Allergic Disorders

( Source: MEDICA.de )

[12/01/2011] Researchers at the University of Gothenburg, Sweden, have developed new methods for analysing medical databases that can be used to identify diagnostic markers more quickly and to personalise medication for allergic disorders. They could also reduce the need for animal trials in clinical studies.Analysis of Medical Database: New Markers for Allergic Disorders - Read more

Chronic Fatigue Syndrome: Not Caused by XMRV

( Source: MEDICA.de )

Not Caused by XMRV [21/12/2010] A virus previously thought to be associated with chronic fatigue syndrome is not the cause of the disease, a detailed study led by UCL scientists has shown. Chronic Fatigue Syndrome: Not Caused by XMRV - Read more

Laboratory: Stem Cells Turned into Complex, Functioning Intestinal Tissue

( Source: MEDICA.de )

Stem Cells Turned into Complex, Functioning Intestinal Tissue [13/12/2010] For the first time, scientists have created functioning human intestinal tissue in the laboratory from pluripotent stem cells.Laboratory: Stem Cells Turned into Complex, Functioning Intestinal Tissue - Read more

Cell Movement: Mechanism Linked to Tumors Becoming More Aggressive

( Source: MEDICA.de )

Mechanism Linked to Tumors Becoming More Aggressive [09/12/2010] Researchers at the University of Georgia have discovered a central switch that controls whether cells move or remain stationary. The misregulation of this switch may play a role in the increased movement of tumor cells and in the aggressiveness of tumors themselves.Cell Movement: Mechanism Linked to Tumors Becoming More Aggressive - Read more

Study: Possibility of Reversing Damage Caused by MS

( Source: MEDICA.de )

Possibility of Reversing Damage Caused by MS [07/12/2010] Damage caused by multiple sclerosis could be reversed by activating stem cells that can repair injury in the central nervous system, a study has shown.Study: Possibility of Reversing Damage Caused by MS - Read more

New Technology: Scientists Map Changes in Genetic Networks Caused by DNA Damage

( Source: MEDICA.de )

Scientists Map Changes in Genetic Networks Caused by DNA Damage [06/12/2010] Using a new technology called "differential epistasis maps," an international team of scientists, led by researchers at the University of California, San Diego School of Medicine, has documented for the first time how a cellular genetic network completely rewires itself in response to stress by DNA-damaging agents. New Technology: Scientists Map Changes in Genetic Networks Caused by DNA Damage - Read more

Immune cells: Incitement to suicide

( Source: MEDICA.de )

Incitement to suicide [01/12/2010] Each of our somatic cells contains a genetic suicide program, which can be activated by patrolling immune cells. Cancer cells avoid this elimination mechanism. Immune cells: Incitement to suicide - Read more

Commentary: Miracles can happen

( Source: MEDICA.de )

Miracles can happen [01/12/2010] Even in patients with terminal cancer, time and again there are miraculous tumor regressions. Such spectacular developments demonstrate what our self-healing powers are capable off in extreme cases. Commentary: Miracles can happen - Read more

Discovery Points: Potential New Strategy for Treating HIV

( Source: MEDICA.de )

Potential New Strategy for Treating HIV [01/12/2010] Scientists at Gladstone Institute of Virology and Immunology have solved a long-standing mystery about HIV infection—namely how HIV promotes the death of CD4 T cells. Discovery Points: Potential New Strategy for Treating HIV - Read more

The immune system‘s memory: “A targeted switch off of only the disease-enhancing memory cells would be desirable“

( Source: MEDICA.de )

“A targeted switch off of only the disease-enhancing memory cells would be desirable“ [01/12/2010] As the core of the adaptive immune system, our memory assumes a central function. The human immune system recognizes a myriad of exogenous agents and scans new pathogens after they invade the body. Subsequently, our immunological memory will remember these pathogens, identify them faster and effectively destroy them. The immune system‘s memory: “A targeted switch off of only the disease-enhancing memory cells would be desirable“ - Read more

Cancer Stem Cell Model: Melanoma Does Not Conform

( Source: MEDICA.de )

Melanoma Does Not Conform [19/11/2010] University of Michigan researchers have determined that most types of melanoma cells can form malignant tumors, providing new evidence that the deadliest form of skin cancer does not conform to the increasingly popular cancer stem cell model. Cancer Stem Cell Model: Melanoma Does Not Conform - Read more

Model for Neural Development: 'Grow Rett Syndrome' in a Petri dish

( Source: MEDICA.de )

'Grow Rett Syndrome' in a Petri dish [18/11/2010] A groundbreaking study revealed that a team of investigators had successfully generated nerve cells using skin cells from four individuals with Rett syndrome. Model for Neural Development: 'Grow Rett Syndrome' in a Petri dish - Read more

Specialised Blood Vessels: Jumpstart and Sustain Liver Regeneration

( Source: MEDICA.de )

[16/11/2010] The liver's unique ability among organs to regenerate itself has been little understood. Now scientists have shed light on how the liver restores itself by demonstrating that endothelial cells - the cells that form the lining of blood vessels - play a key role.Specialised Blood Vessels: Jumpstart and Sustain Liver Regeneration - Read more

Prostata Cancer: Therapy for Patients with a Deadly Subset

( Source: MEDICA.de )

[09/11/2010] A monoclonal antibody targeting a well known cell surface protein inhibited prostate cancer growth and metastasis in an aggressive form of the disease that did not respond to hormone therapy, according to a study by researchers with the UCLA Department of Urology and UCLA’s Jonsson Comprehensive Cancer Center.Prostata Cancer: Therapy for Patients with a Deadly Subset - Read more

Atherosclerosis: Body´s Bacteria Affect the Outcome

( Source: MEDICA.de )

[18/10/2010] New findings suggesting that bacteria in the mouth and/or intestine can affect the the outcome pathogenesis of atherosclerosis and lead to new treatment strategies, reveals research from the University of Gothenburg, Sweden.Atherosclerosis: Body´s Bacteria Affect the Outcome - Read more

Cancer: Cells Switch Their Profile

( Source: MEDICA.de )

Cells Switch Their Profile [18/10/2010] Scientists at the University of East Anglia have made an important breakthrough in the way anti-cancer drugs are tested.Cancer: Cells Switch Their Profile - Read more

Nanoparticles: Sneaking Spies Into a Cell's Nucleus

( Source: MEDICA.de )

Sneaking Spies Into a Cell's Nucleus [30/09/2010] Duke University bioengineers have not only figured out a way to sneak molecular spies through the walls of individual cells, they can now slip them into the command center – or nucleus – of those cells, where they can report back important information or drop off payloads.Nanoparticles: Sneaking Spies Into a Cell's Nucleus - Read more

Interaction With Neighbors: Neuronal field simulates brain activity

( Source: MEDICA.de )

Neuronal field simulates brain activity [29/09/2010] RUB Scientists of the Bernstein Group for Computational Neuroscience developed a computational model, which allows a mathematical description of far reaching interactions between cortical neurons. Interaction With Neighbors: Neuronal field simulates brain activity - Read more

Human Autoimmune Disease: Researchers Unlock Mystery

( Source: MEDICA.de )

[22/09/2010] Researchers at Columbia University Medical Center have identified a defect in the T cell regulatory pathway which normally controls autoreactive T cells that attack the body’s own tissues. A majority of people with Type 1 Diabetes who were tested in the study were found to have the newly-identified cellular/molecular defect. The researchers were able to successfully correct the defect in-vitro.Human Autoimmune Disease: Researchers Unlock Mystery - Read more

HIV: Mechanism Discovered to Increase Immune Response

( Source: MEDICA.de )

Mechanism Discovered to Increase Immune Response [10/09/2010] A team of scientists has discovered a sensor in dendritic cells that recognizes HIV, spurring a more potent immune response by the sentinels to the virus. HIV: Mechanism Discovered to Increase Immune Response - Read more

New Infrared Light: New Frontier in Fighting Cancer

( Source: MEDICA.de )

New Frontier in Fighting Cancer [02/09/2010] A "game-changing" technique using near infrared light enables scientists to look deeper into the guts of cells, potentially opening up a new frontier in the fights against cancer and many other diseases.New Infrared Light: New Frontier in Fighting Cancer - Read more

Diabetics: Antibiotic May Reduce Stroke Risk And Injury

( Source: MEDICA.de )

[30/08/2010] A daily dose of an old antibiotic may help diabetics avoid a stroke or at least minimise its damage, Medical College of Georgia researchers report.Diabetics: Antibiotic May Reduce Stroke Risk And Injury - Read more

Gonorrhoeae Bacteria: Waiting For The Right Moment

( Source: MEDICA.de )

Waiting For The Right Moment [26/08/2010] Pathogens make themselves feel at home in the human body, invading cells and living off the plentiful amenities on offer. Gonorrhoeae Bacteria: Waiting For The Right Moment - Read more

Immune Genes: Key in Parkinson's Disease

( Source: MEDICA.de )

[17/08/2010] The immune system may have a key role in the development of Parkinson's disease, say US researchers. Immune Genes: Key in Parkinson's Disease - Read more

Aggressive Breast Cancer: Genes Associated

( Source: MEDICA.de )

[16/08/2010] Researchers at the University of Gothenburg, Sweden, have for the first time identified 12 genes that could be associated with aggressive breast tumours. The discovery could result in more reliable prognoses and better treatment strategies for patients.Aggressive Breast Cancer: Genes Associated - Read more

Virtually Identical: Human Embryonic Stem Cells and Reprogrammed Cells

( Source: MEDICA.de )

[09/08/2010] Human embryonic stem cells and adult cells reprogrammed to an embryonic stem cell-like state—so-called induced pluripotent stem or iPS cells—exhibit very few differences in their gene expression signatures and are nearly indistinguishable in their chromatin state, according to researchers. Virtually Identical: Human Embryonic Stem Cells and Reprogrammed Cells - Read more

Healthy Teeth: Gene Brings Teeth in Shape

( Source: MEDICA.de )

Gene Brings Teeth in Shape [06/08/2010] No healthy teeth without this gene: if during tooth formation (odontogenesis) the so-called Jagged2 gene is inactivated, and hence the Notch signalling pathway interrupted, tooth crowns will be malformed and enamel will be lacking. Healthy Teeth: Gene Brings Teeth in Shape - Read more

Inflammatory Bowel Disease: Potential Key Regulator Detected

( Source: MEDICA.de )

[04/08/2010] Research into inflammatory bowel disease (IBD) led by UCD Conway Institute scientists has identified a key regulator involved in maintaining the functional integrity of the gut lining. Inflammatory Bowel Disease: Potential Key Regulator Detected - Read more

Protein for Iron Balance: Supply and Demand

( Source: MEDICA.de )

Photo: Mitochondria in a normal cell [04/08/2010] Most organisms need iron to survive, but too much iron is toxic, and can cause fatal organ failure. The same is true inside cells, where iron balance must also be maintained. Scientists have now identified proteins that ensure iron balance.Protein for Iron Balance: Supply and Demand - Read more

Coral Pigment: Helps to Observe Protein Movement

( Source: MEDICA.de )

Helps to Observe Protein Movement [28/07/2010] Scientists have shown that a variant form of a fluorescent protein (FP) originally isolated from a reef coral has excellent properties as a marker protein for super-resolution microscopy in live cells. Coral Pigment: Helps to Observe Protein Movement - Read more

Math Model: Colon Inflammation Singles out Dangerous Immune Cells

( Source: MEDICA.de )

[23/07/2010] Scientists have constructed a mathematical and computational model of inflammatory bowel disease that allows researchers to simulate the cellular and molecular changes underlying chronic inflammation in humans. Math Model: Colon Inflammation Singles out Dangerous Immune Cells - Read more

Cancer: Studying Cells in 3-D

( Source: MEDICA.de )

Photo: Cancer Cell [23/06/2010] Showing movies in 3-D has produced a box-office bonanza in recent months. Could viewing cell behaviour in three dimensions lead to important advances in cancer research? Cancer: Studying Cells in 3-D - Read more

Research: Novel Enzyme Linked to Cancer Cell Migration

( Source: MEDICA.de )

Novel Enzyme Linked to Cancer Cell Migration [01/06/2010] Scientists at the University of California, San Diego have identified a previously unknown kinase that regulates cell proliferation, shape and migration, and may play a major role in the progression or metastasis of cancer cells. Research: Novel Enzyme Linked to Cancer Cell Migration - Read more

Breast Cancer: Shortened Therapy Leads to Success

( Source: MEDICA.de )

Shortened Therapy Leads to Success [01/06/2010] You have breast cancer. A sentence, that is life changing and one that more and more women get to hear. Yet there is reason for hope: According to early research results, a new treatment method could prove more effective than the standard therapy – and it could also prevent women from having nasty side effects. Breast Cancer: Shortened Therapy Leads to Success - Read more

Development: Picturing infertility

( Source: MEDICA.de )

[19/05/2010] Scientists from Ruhr-Universität Bochum have developed a non-invasive technique that within seconds can distinguish healthy fertile and infertile sperm cells by collecting the spectral chemical fingerprint. The method has the potential for a novel fertility technology and a test scheme which does not only rely on morphological characteristics, but also utilizes chemical signatures. Development: Picturing infertility - Read more

Genome: Profile Tumor Cells from Small Samples

( Source: MEDICA.de )

[14/05/2010] Researchers have developed a technique for analyzing the genome of single tumor cells. This allows them to study how tumors develop. It has the potential to help doctors identify dangerous tumor cells from small samples.Genome: Profile Tumor Cells from Small Samples - Read more

Microscopy: A "Fat Forward" Research Tool

( Source: MEDICA.de )

[12/05/2010] Researchers in tissue engineering have developed a "fat finder", a microscope-based cell scanner, that can help scientists accelerate their research into new fat-melting drugs.Microscopy: A "Fat Forward" Research Tool - Read more

Stem Cells: In Search of a Master Controller

( Source: MEDICA.de )

[10/05/2010] New research suggests that a closely connected trio of regulatory proteins are the “master regulators” in hematopoietic stem cells (HSCs), the self-renewing cells the body uses to make new blood cells.Stem Cells: In Search of a Master Controller - Read more

Brain Cancer: Tumour Cells Need Different Treatment

( Source: MEDICA.de )

Tumour Cells Need Different Treatment [15/04/2010] Cancer cells leftover in the brain after surgery have different properties than the cells in the centre of the tumour, researchers found out. They also react differently to radiation therapy and chemotherapeutic substances.Brain Cancer: Tumour Cells Need Different Treatment - Read more

DNA: Probing Gene Activation

( Source: MEDICA.de )

Probing Gene Activation [13/04/2010] Researchers have developed a new method to investigate the discrete steps necessary to turn on individual genes. The finding allows scientists to analyse the unfolding of DNA, a process required for gene activation.DNA: Probing Gene Activation - Read more

Disinfection: “Plasma Makes Bacteria Cell Walls Burst“

( Source: MEDICA.de )

[22/03/2010] Never wash without using soap – this is a slogan that surgeons should keep in mind at work. Hygiene of the future may look quite differently though, according to recent physicist’s findings. Disinfection: “Plasma Makes Bacteria Cell Walls Burst“ - Read more

T Cells: Surprise for Stroke Researchers

( Source: MEDICA.de )

 [16/03/2010] Strokes are less damaging if certain immune cells are absent in the blood. This previously unknown mechanism will be presented by researchers from the University of Würzburg.T Cells: Surprise for Stroke Researchers - Read more

Nano Technique: Insight into Failing Heart Cells

( Source: MEDICA.de )

Insight into Failing Heart Cells [26/02/2010] Researchers have been able to see how heart failure affects the surface of an individual heart muscle cell in minute detail, using a new nanoscale scanning technique.Nano Technique: Insight into Failing Heart Cells - Read more

Heart: Enzyme Critical for Function

( Source: MEDICA.de )

[25/02/2010] Scientists are reporting data to show that the enzyme calcineurin is critical in controlling normal development and function of heart cells, and that loss of the protein leads to heart problems and death in genetically modified mice.Heart: Enzyme Critical for Function - Read more

Brain: How Nerve Cells Grow

( Source: MEDICA.de )

How Nerve Cells Grow [24/02/2010] Brain researcher Hiroshi Kawabe has discovered the workings of a process that allows nerve cells in the brain to grow and form complex networks.Brain: How Nerve Cells Grow - Read more

Liver: New Screening System for Hepatitis C

( Source: MEDICA.de )

New Screening System for Hepatitis C [12/02/2010] A newly designed system of identifying molecules for treating hepatitis C might enable scientists to discover novel and effective therapies for the disease of the liver, according to a researcher.Liver: New Screening System for Hepatitis C - Read more

HIV/Aids: Tracing Mutations that Lead to Drug Resistance

( Source: MEDICA.de )

Tracing Mutations that Lead to Drug Resistance [09/02/2010] Chemists and statisticians have developed a new way to trace mutations in HIV that lead to drug resistance.HIV/Aids: Tracing Mutations that Lead to Drug Resistance - Read more

Nanoparticles: Promising for Combating Cancer

( Source: MEDICA.de )

Promising for Combating Cancer [04/02/2010] Scientists have further developed a potential new treatment against cancer that uses magnetic nanoparticles to attach to cancer cells, removing them from the body. Nanoparticles: Promising for Combating Cancer - Read more

Rheumatism: New 'Suicide' Molecule Halts Arthritis

( Source: MEDICA.de )

New 'Suicide' Molecule Halts Arthritis [29/01/2010] A researcher has invented a novel way to halt and even reverse rheumatoid arthritis in mice. He developed an imitation of a suicide molecule that floats undetected into overactive immune cells responsible for the disease.Rheumatism: New 'Suicide' Molecule Halts Arthritis - Read more

Leukaemia: Cells Can Suppress Immune Reaction

( Source: MEDICA.de )

Cells Can Suppress Immune Reaction [24/10/2008] In the future, bone marrow transfer to patients with leukaemia could be more secure. Mice experiments have shown that certain cells of the immune system can suppress the dangerous side effects resulting from treatment. Leukaemia: Cells Can Suppress Immune Reaction - Read more

Food Safety: Detecting Bacteria With Fish Cells

( Source: MEDICA.de )

[26/09/2008] Microbiologists have developed a possible new way to detect illness-causing bacteria. The approach builds on the colour changes in pigment-bearing cells from Siamese fighting fishes. Food Safety: Detecting Bacteria With Fish Cells - Read more

Chronic Infection: Hepatitis B Virus Triggers Cell ‘Suicide’

( Source: MEDICA.de )

[11/04/2008] Scientists from the University College London (UCL) have identified a key difference between people who can fight the Hepatitis B virus (HBV) off successfully and those who fail to do so.Chronic Infection: Hepatitis B Virus Triggers Cell ‘Suicide’ - Read more

 
 

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